Pharmacodynamics 1

Question 1

What is Drug action

Answer 1

Drug action refers to the mechanism with which a drug produce desirable or undesirable effect in the body

Question 2

Types of drug action

Answer 2

CRIDS
S- stimulation
D- depression
I- irritation
R- replacement
C- cytotoxic

Question 3

Stimulation meaning

Answer 3

Selective enhancement of specific activity done by a specialized cells e.g adrenaline in cardiac cells

Question 4

Depression

Answer 4

Involves the selective diminution of specific activity done by a specialized cell
E.g Lisinopril for hypertension

Question 5

Mechanism of drug action

Answer 5

Physical
Chemical
Biochemistry

Question 6

Types of receptors

Answer 6

Ligand gated ion channels
G protein coupled receptor
Enzyme-linked receptors
Intercellular receptors

Question 7

Drug receptor outcome

Answer 7

F- full agonist
A- antagonist
P- partial agonist
I- inverse agonist

Question 8

What is a ligand

Answer 8

A ligand is any molecule which selectively binds itself to a particular receptor

Question 9

Define Affinity

Answer 9

This can be defined as the strength of the reversible reaction between a drug and it’s receptor has measured by the dissociation constant
It is the affinity of one for the other

Question 10

Define intrinsic activity

Answer 10

Capacity to induce a functional change in the receptor