Pharmaceutical Measurement Flashcards
8-27 lesson
1
Q
graduate capacity
A
5 to 1000mL
2
Q
smallest quantity in mg equation (also used to find SR, AE%)
A
100% x SR (mg) / AE (%)
3
Q
explain how you would find 5mg of a drug
A
- Find multiple (MF) that is going to be used. remember it has to equal a whole number. You want to obtain a number that will be greater than 120mg.
*5mg (given in problem) x MF = drug. (5mg x 25=125mg) - Find the amount of diluent being used by finding the total mixture. As the final product, you want 120mg (MWA).
*120mg x MF = total mixture (120mg x 25 = 3000mg) - Using the total mixture, find the diluent.
- total mixture - drug (in step 1)= diluent (3000-125=2875)
- find the measurements for aliquot portion. currently we have the portions of 25, we need to find it of one.
*1/MF x drug = drug - 1/MF x diluent = diluent (1/25 x 125mg = 5 - 1/25 x 2875=115)
Therefore, there is 5mg of drug and 115mg of diluent.
4
Q
explain how you would find 5 doses of 20mg each
A
- Find MF by dividing the dose into the MWQ (120mg)
- 120/dose=MF (120/20=6)
- Find diluent by subtracting drug dose from MWQ and multipling it by MF
*120 - 20mgx6= 600mg
Therefore, 600mg is to be mixed with 120mg of the drug.
5
Q
explain how you would measure 0.5mL of a drug solution in 10mL graduate calibrated from 2 to 10mL in 1-mL divisions.
A
- Find MF, remember it has to be a whole number
- 0.5mL x 4 = 2mL
- Find the amount of dilute by finding final mixture
- 2mL x 4 = 8mL
- Using final mixture, find dilute
- 8mL - 2mL = 6mL
- find the measurements for aliquot portion. currently we have the portions of 4, we need to find it of one.
- 8ml x 1/4 = 2mL final mixture
6
Q
percentage error equation IN weight
A
% error = error x 100% / quantity desired
7
Q
percentage error equation IN volume
A
% error = (error difference) x 100% / volume desired
error difference is what you measured - what you had to measure
8
Q
A
