Pharmaceutical factors affecting drugs Flashcards
1
Q
What is bioequivalence assessed by
A
Time to peak plasma level (tmax)
peak plasma level (Cmax)
Bioavailability (F)
2
Q
Can you prescribe different brands of same drug
A
certain drugs should be prescribed as the same formulation
3
Q
What is EC and SR
A
Enteric Coat
Sustained release
4
Q
What is the purpose of modified or sustained release preparations
A
Reduce rate of absorption and prolong action
Deliver drug to specific region of GI tract
5
Q
Oramorph vs Morphogesic SR
A
Oramorph- oral suspension for immediate pain relief
Morphagesic SR- sustained release provides longer pain relief
6
Q
What are GTN and fentanyl applied as and why
A
Provides sustained release
they are formulated with ethanol to enhance skin penetration