Pharmaceutical factors affecting drugs Flashcards

1
Q

What is bioequivalence assessed by

A

Time to peak plasma level (tmax)

peak plasma level (Cmax)

Bioavailability (F)

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2
Q

Can you prescribe different brands of same drug

A

certain drugs should be prescribed as the same formulation

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3
Q

What is EC and SR

A

Enteric Coat

Sustained release

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4
Q

What is the purpose of modified or sustained release preparations

A

Reduce rate of absorption and prolong action

Deliver drug to specific region of GI tract

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5
Q

Oramorph vs Morphogesic SR

A

Oramorph- oral suspension for immediate pain relief

Morphagesic SR- sustained release provides longer pain relief

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6
Q

What are GTN and fentanyl applied as and why

A

Provides sustained release

they are formulated with ethanol to enhance skin penetration

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