Pharmaceutical Classifications and common cardiac/diabetes drugs Flashcards
Analgesic
Mild to severe pain reliever
Antihelmintic
Kills parasites and their eggs
Antiasthmatic
Prevents asthma, treats asthma attacks
Anticholinergic
Blocks ANS parasympathetic impulses, lessens spasm of muscles in GI and bladder. Also treats asthma, COPD, dizziness and motion sickness, high blood pressure, Parkinson’s disease.
• Side effects: Dry mouth, blurred vision, constipation, drowsiness, sedation, hallucination, memory impairment, difficulty urinating, confusion, delirium, decreased sweating, decreased saliva.
Anticonvulsant
Prevents, controls, or relieves seizures
Antidiabetic
Treats diabetes
Antacid
Neutralizes stomach acid
Antiarrhythmic
Normalizes heartbeat
Antibiotics
Prevents bacterial reproduction
Anticoagulant
Prevents blood from clotting
Anti-depressant (Tricyclic, MAOI, SSRI, SNRI)
Relieves depression
Antidiarrheal
Relieves diarrhea
Antiemetic
Prevents or relieves vomiting and nausea
Antihistamine
Counteracts histamine, relieves allergies
Anti-inflammatory
Reduces inflammation
Antineoplastic
Destroys cancer cells (poisons them)
Anti-pyretic
Fever reducer
Antitussive
Reduces cough
Antifungal
Destroys or prevents the growth of fungi
Antihypertensive
Reduces blood pressure
Antilipemic
Lowers blood lipids/triglycerides
Antipsychotic
Controls psychosis
Antiseptic
Inhibits microorganism growth and spreading
Bronchodilator
Dilates bronchi
Cathartic (laxative)
Alleviates constipation
Decongestant
Relieves nasal congestion and inflammation
Expectorant
Liquefies bronchi mucous
Hormone replacement (HRT)
Resolves hormone deficiency
Hormone replacement
Resolves hormone deficiency
Muscle relaxant
Relaxes skeletal muscles
Contraceptive
Prevents pregnancy
Oral or physical devices
Diuretic
Increases urine output and reduces blood pressure and cardiac output
Hemostatic
Stops bleeding
Hypnotic (sedative)
Relaxation or sleep
Hypnotic (Sedative)
Relaxation or sleep
Mydriatic
Constricts eye or nasal vessels (dilates pupils)
Stimulant
Decreases appetite, increases brain activity and sympathetic activity
Vasodilator
Dilates blood vessels to decrease blood pressure
Vasoconstrictor
Constricts blood vessels to increase blood pressure
Anti-metabolites
A chemical that inhibits metabolites
Beta Blockers (–olol)
Beta-blockers are drugs that bind to beta-adrenoceptors and thereby block the binding of norepinephrine and epinephrine to these receptors. Used to treat: angina • atrial arrhythmias • coronary artery disease • heart failure • hypertension • early post-traumatic stress disorder • Metoprolol and atenolol, which are cardioselective, are the most widely used β blockers in the treatment of hypertension.
Beta blockers side effects
Common side effects of beta blockers can include:
Cold hands or feet
Fatigue
Weight gain
Calcium-Channel Blockers (CCBs) ( –ine)
Calcium channel blocking agents restrict the amount of calcium entering cardiac and smooth muscle cells by blocking voltage-gated calcium channels. This causes blood vessels to relax and widen (vasodilate), improves oxygen supply to the heart, and lowers blood pressure.
Side effects of CCBs
constipation, nausea, headache, rash, edema, hypotension, drowsiness, dizziness
ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS
Reduce angiotensin II levels • reduce vasoconstriction and aldosterone secretion • increase bradykinin
Side effects ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS
Toxicity: COUGH,
angioedema • hyperkalemia • renal impairment • teratogenic
ANGIOTENSIN RECEPTOR BLOCKERS (ARBS)
Same as ACE inhibitors but no increase in bradykinin
Side effects of ARBS
less cough than ACE-i; angioedema • hyperkalemia • renal impairment • teratogenic
Statins
Statins (also called HMG-CoA reductase inhibitors) block an enzyme called HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) that is involved in the synthesis of mevalonate, a naturally occurring substance that is then used by the body to make sterols, including cholesterol.
By inhibiting this enzyme, cholesterol and LDL-cholesterol production is decreased.
The most common side effects reported with statins include:
side effects reported with statins : A headache belching or excessive gas constipation heartburn, indigestion, nausea or stomach discomfort hoarseness lower back or side pain muscle pain, tenderness, or weakness
Antiplatelets
Aspirin, Clopidogrel (Plavix)
Side effects of Antiplatelets
Diarrhea, rash, itching, abdominal pain, headache, chest pain, muscle aches, dizziness.
Anti-arrhythmics
amiodarone (Cordarone, Pacerone), CCBs, B-blockers, Anticoagulants etc.
Side effects of anti-arrhythmics
dizziness, blurred vision, anorexia, unusual taste, fatigue, nausea and vomiting.
Vasodilators:
The oral vasodilators, hydralazine and minoxidil, which are used for long-term outpatient therapy of hypertension
Side effects of Vasodilators:
lightheadedness, irregular heart rate, headache, diaphoresis, anorexia, nausea…..
Oral hypoglycemics:
DM type 2: THIAZOLIDINEDIONES, GLUCAGON-LIKE POLYPEPTIDE-1 (GLP-1) RECEPTOR AGONISTS, ALPHA-GLUCOSIDASE INHIBITORS, BIGUANIDES, SULFONYLUREAS
THIAZOLIDINEDIONES
• Pioglitazone, rosiglitazone
DM type 2: Reduce insulin resistance. Toxicity: Fluid retention, edema, anemia, weight gain, macular edema, bone fractures in women • cannot use if CHF, hepatic disease
Megitinides
DM type 2: In patients with functioning beta cells, lower blood sugar by stimulating pancreatic secretion of insulin
SULFONYLUREAS
Glipizide • Glimepiride
DM type 2: Reduce circulating glucose in patients with functioning beta cells. Toxicity: Hypoglycemia, weight gain
BIGUANIDES
• Metformin
DM type 2: Decreases circulating glucose. Toxicity: Gastrointestinal symptoms, lactic acidosis (rare) • cannot use if impaired renal/hepatic function • congestive heart failure (CHF), hypoxic/acidotic states, alcoholism
ALPHA-GLUCOSIDASE INHIBITORS
• Acarbose, miglitol
DM type 2: Reduce conversion of starch and disaccharides to monosaccharides • reduce postprandial hyperglycemia. Toxicity: Gastrointestinal symptoms • cannot use if impaired renal/hepatic function, intestinal disorders
GLUCAGON-LIKE POLYPEPTIDE-1 (GLP-1) RECEPTOR AGONISTS
DM type 2: Reduce post-meal glucose excursions: Increase glucosemediated insulin release, lower glucagon levels, slow gastric emptying, decrease appetite. Toxicity: Nausea, headache, vomiting, anorexia, mild weight loss, pancreatitis