Drug-Mineral-Organ Effects Flashcards

1
Q

Metoclopramide

A

Increases GI motility, decreases food absorption

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2
Q

Opioids, anticholinergic

A

Decreases GI motility, can lead to constipation (RED FLAG WARNING)

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3
Q

Diuretics (thiazides, corticosteroids)

A

Can deplete K+

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4
Q

Laxatives

A

May deplete K+

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5
Q

Cortisol, aldosterone, deoxycorticosterone

A

Causes marked sodium and water retention

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6
Q

Sulfonylureas and lithium

A

Impairs thyroid uptake and release of iodine (causes thyroid problems)

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7
Q

Oral contraceptives

A

Lowers zinc levels

Increases copper levels

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8
Q

Certain Antibiotics (tetracyclines)

A

Reduces iron absorption from food

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9
Q

Ethanol

A

Impairs thiamin, niacin, pyridoxine (B vitamins)

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10
Q

Ethanol and oral contraceptives

A

Inhibits folate absorption

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11
Q

Phenytoin, primidone

A

Causes folate (folic acid/ B9) deficiency

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12
Q

Folate vitamins

A

Makes phenytoin less effective

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13
Q

Anticonvulsants

A

Can cause vitamin D deficiency

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14
Q

Ethanol, oral contraceptives, aminosalicyclic acid, slow-release potassium iodide, colchicine, trifluoperazine,

A

Interfere with absorption of B12

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15
Q

OCPs with a high progestin dose

A

Can cause depression (probably because of metabolically induced tryptophan deficiency)

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16
Q

Orlisat

A

Prevents fat absorption

17
Q

Chloramphenicol, tetracycline

A

Decreases protein metabolism

18
Q

Adrenal corticosteroids, ethanol, growth hormone, oral contraceptives, vitamin D

A

Increases blood lipid levels

19
Q

Aspirin, colchicine, glucagon, niacin, statins

A

Decreases blood lipid levels

20
Q

Antibiotics, fiber, digoxin, glucagon, fluoxetine, morphine

A

Decreases appetite

21
Q

Ethanol, anti-histamine, corticosteroids, insulin, psychoactive drugs, thyroid hormones

A

Increases appetite