Pharma Study Flashcards
Tolerance
Natural or developed ability to resist effects of the continued or increasing use of a drug
Tonicity
Refers to the concentration of chems. in that solution
Sterility
Solution must be free from bacterial contamination
Stability
Solutions must be reasonably stable and not deteriorate or loose their effectiveness
Penetration
Eye drops penetrate the eye directly thru cornea and into ac of eye
3 principal delivery systems
Topical, oral, injection
Topical
Meds are applied directly to the surface of the eye or surrounding skin
Oral
Meds are taken by mouth
Injectable
Meds are injected w hypodermic needle into or around the eye or into different part of body
Four principal topical delivery systems
Solutions, suspensions, ointments+gels, soluble drugs inserts
Oral [ex]
Tablets,capsule, liquids
Injections [ex]
Intravitreal, subconjunctival, retrobulbar
Solutions
Placed directly in the eye - usually instilled in conjunctival sac
Suspensions
Liquid vehicles which “particles” are suspended- must shake well - may contain preservative to inhibit growth of unwanted bacteria during storage
Ungs
Greasy or oilly - remains in contact for prolonged time - typically bedtime therapy- difficult to apply [ointment]