Pharma Study Flashcards

1
Q

Tolerance

A

Natural or developed ability to resist effects of the continued or increasing use of a drug

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2
Q

Tonicity

A

Refers to the concentration of chems. in that solution

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3
Q

Sterility

A

Solution must be free from bacterial contamination

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4
Q

Stability

A

Solutions must be reasonably stable and not deteriorate or loose their effectiveness

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5
Q

Penetration

A

Eye drops penetrate the eye directly thru cornea and into ac of eye

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6
Q

3 principal delivery systems

A

Topical, oral, injection

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7
Q

Topical

A

Meds are applied directly to the surface of the eye or surrounding skin

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8
Q

Oral

A

Meds are taken by mouth

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9
Q

Injectable

A

Meds are injected w hypodermic needle into or around the eye or into different part of body

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10
Q

Four principal topical delivery systems

A

Solutions, suspensions, ointments+gels, soluble drugs inserts

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11
Q

Oral [ex]

A

Tablets,capsule, liquids

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12
Q

Injections [ex]

A

Intravitreal, subconjunctival, retrobulbar

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13
Q

Solutions

A

Placed directly in the eye - usually instilled in conjunctival sac

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14
Q

Suspensions

A

Liquid vehicles which “particles” are suspended- must shake well - may contain preservative to inhibit growth of unwanted bacteria during storage

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15
Q

Ungs

A

Greasy or oilly - remains in contact for prolonged time - typically bedtime therapy- difficult to apply [ointment]

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16
Q

Inserts

A

Placed in the corner of the lower conjunctiva

17
Q

Retrobulbar

A

Inject. Med thru the skin of lower lid - paralyze eom + anesthetizes

18
Q

Intravitreal

A

Inject. Into eye

19
Q

Eye drop + ointment installation

A

Was or sanitize hands - 20 secs

*warn pt ointment blur vision bc it smears the cornea

20
Q

Eye drops cont.

A

Eye drops follow correct procedures - verify physicians orders 2x - prepare patient for stinging/burning - avoid cross contamination- never rub - wipes excess drops w fresh tissue - wait 3-5 mins between eye meds

21
Q

Complications of locally administered meds

A

Allergic reaction
Toxic reaction
Discoloration of eye
Undesirable side effects
Idiosyncrasy [abnormalities]
Loss of effect by inactivation
Spread of infection

22
Q

Induction period

A

Delay period between the reaction to the use of particular drug and the development of a state of hypersensitivity

23
Q

Punctal occlusion

A

Procedure treats des and other conditions by blocking tear drainage system

24
Q

Mydriatics

A

Serve to dilate pupils - by stimulating the iris dilator muscle

25
Q

Cycloplegics

A

Act on iris by dilating pupil + ciliary body paralyzing fine focusing muscles so eye is no longer able to accommodate for nv

May sting slightly when administered in eye

26
Q

Dyes - stains

A

Highlight defects [temp stains cells]
Cheif use - to elevate ocular surface

27
Q

Topical/injected anesthetics

A

Drug causes temp deadening of nerve
Loss of feel in surrounding tissue

**don’t rub numbed eye can b easily scratched w out pt being aware of dmg

28
Q

Therapeutic meds

A

Miotics
Antimicrobial
Anti allergic/inflamm
Decongestants
Lubricants

29
Q

Miosis

A

Pupillary constriction- reduction of light entering eye

Contraction of ciliary body muscle

30
Q

Antimicrobials

A

Anti…

Biotic- treat infection
Viral - treat virus infection
Fungal - treat fungal infection

31
Q

Decongestants

A

Constricting superficial blood vessels in conjunctiva

Reduce redness

  • blood vessels may become more conjested than b4 taking drug
32
Q

Prescriptions parts

A

Heading
Prescription
Physicians signature

33
Q

Aqueous humor

A

Clear, watery fluid that fills the ac and posterior chambers within the front part of the eye