pharma

Question 1

Treatment for IR?

Answer 1

• Metformin
  -Thiazolidindiones
  improve the receptor sensitivity

Question 2

what is the most common drug for T2DM ?

Answer 2

sulfonylureas

Question 3

classifications of sulfonylureas?

Answer 3

1st gen : tolbutamide, chlorpropamide, acetohexamide - not much used cuz may induces hypoglycemia + not for renal impairment

2nd gen: Glibenclamide, Glipizide, Gliclazide
3rd gen: glimepiride

Question 4

enzyme that converts 2 iodide ions into iodine molecules to be utilized by the thyroid gland?

Answer 4

thyroperoxidase enzyme

Question 5

pregnant women medications?

Answer 5

preferable not to treat ant pregnant women with any medication unless its very indicated or after delivery

Question 6

which medication in hyperthyroidism treatment is FINE to use with pregnant women and why?

Answer 6

Propylthiouracil, a part of thiouracil family
- because it has more affinity to plasma proteins and does not cross placental barrier, and will not go out to the milk