Pharma Flashcards
define sensitivity in terms of drugs
sensitivity is the proportion of people who have the disease who will have a positive result
AKA the true positive rate
define specificity in terms of drugs
specificity is the proportion of people who do not have the disease who will have a negative result
AKA the true negative rate
sensitivity is therefore a way of seeing how good the test is at…
how good the test is at identifying people with the disease
specificity is therefore a way of seeing how good the test is at…
how good the test is at identifying which people don’t have the disease
how do you calculate sensitivity
those who have the disease and test positive
/
those with disease that test positive or negative
how do you calculate sensitivity in terms of tp,fp,tn,fn
true positives
/
true positives and false negatives
how do you calculate specificity
don’t have disease, test negative
/
don’t have disease, test positive or negative
how do you calculate specificity in terms of tp,fp,tn,fn
true negatives
/
true negatives and false positives
what is the positive predictive value
probability a positive test means you have the disease
ie likelihood the positive test is accurate
how is the positive predictive value calculated
true positives
/
true positives and false positives
what is the negative predictive value
probability a negative test means you don’t have the disease
ie likelihood a negative test is accurate
how do you calculate the negative predictive value
true negatives
/
true negatives and false positives
pharmacokinetics is
what your body does to a drug
pharmacodynamics is
what the drug does to your body
what are the 4 components of pharmacokinetics
absorption
distribution
metabolism
excretion
