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Step 1 First Aid > Pharm Side Effects > Flashcards

Pharm Side Effects Flashcards

1
Q

Coronary vasospasm

A

Cocaine, sumatriptan, ergot alkaloids

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2
Q

Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, Ca channel blockers (VANC)

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3
Q

Dilated cardiomyopathy

A

Anthracyclines (doxorubicin, daunorubicin), prevent with dexrazoxane

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4
Q

Torsades de pointes

A

Class III (sotalol) and class IA (quinidine) antiarrhythmics, macrolide antibiotics, antipsychotics, TCAs

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5
Q

Adrenocortical insufficiency

A

HPA suppression secondary to glucocorticoid withdrawal

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6
Q

Hot flashes

A

Tamoxifen, clomiphene

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7
Q

Hyperglycemia

A

Tacrolimus, Protease inhibitors, Niacin, HCTZ, Corticosteroids (Taking Pills Necessitates Having blood Checked)

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8
Q

Hypothyroidism

A

Lithium, amiodarone, sulfonamides

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9
Q

Acute cholestatic hepatitis, jaundice

A

Erythromycin

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10
Q

Diarrhea

A

Metformin, Erythromycin, Colchicine, Orlistat, Acarbose (Might Excite Colon On Accident)

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11
Q

Focal to massive hepatic necrosis

A

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen (Liver HAVAc)

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12
Q

Hepatitis

A

Rifampin, isoniazid, pyrazinamide, statins, fibrates

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13
Q

Pancreatitis

A

Didanosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (Drugs Causing A violent Abdominal Distress)

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14
Q

Pseudomembranous colitis

A

Clindamycin, ampicillin, cephalosporins – CLAMP your Ass

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15
Q

Agranulocytosis

A

Ganciclovir, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil (Gangs CCCrush Myeloblasts and Promyelocytes)

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16
Q

Aplastic anemia

A

Carbamazepine, Methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil (Can’t Make New Blood Cells Properly)

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17
Q

Direct Coombs-positive hemolytic anemia

A

Methyldopa, penicillin

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18
Q

Gray baby syndrome

A

Chloramphenicol

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19
Q

Hemolysis in G6PD deficiency

A

Isoniazid, Sulfonamids, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin (Hemolysis IS D PAIN)

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20
Q

Megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs (Having a BLAST with PMS)

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21
Q

Thrombocytopenia

A

Heparin

22
Q

Thrombotic complications

A

OCPs, hormone replacement therapy

23
Q

Fat redistribution

A

Protease inhibitors, Glucocorticoids (Fat PIG)

24
Q

Gingival hyperplasia

A

Phenytoin, Ca channel blockers, cyclosporine

25
Q

Hyperuricemia (gout)

A

Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine (Painful Tophi and Feet Need Care)

26
Q

Myopathy

A

Fibrates, niacin, colchicine, hydroxychloroquine, interferon-a, penicillamine, statins, glucocorticoids

27
Q

Osteoporosis

A

Corticosteroids, heparin, aromatase inhibitors, PPIs

28
Q

Photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines, 5-FU (SAT For Photo)

29
Q

Rash (Stevens-Johnson syndrome)

A

Anti-epileptic drugs (especially lamotrigine), allopurinol, sulfa drugs, penicillin (sulfas, cilins, seizures, and allopurinol)

30
Q

SLE-like syndrome

A

Sulfa drugs, Hydralazine, Isoniazid, Procainamide, Phenytoin, Etanercept (Having lupus is SHIPP-E) — Have anti-histone antibodies

31
Q

Teeth discoloration

A

Tetracyclines

32
Q

Tendonitis, tendon rupture, and cartilage damage

A

Fluoroquinolones

33
Q

Cinchonism

A

Quinidine, quinine

34
Q

Parkinson-like syndrome

A

Antipsychotics, Reserpine, metoclopramide (Cogwheel rigidity of ARM)

35
Q

Seizures

A

Isoniazid (vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Enflurane (With seizures, I BItE my tongue)

36
Q

Tardive dyskinesia

A

Antipsychotics, metoclopramide

37
Q

Diabetes insipidus

A

Lithium, demeclocycline

38
Q

Fanconi syndrome

A

Expired tetracycline

39
Q

Hemorrhagic cystitis

A

Cyclophoshpamide, ifosfamide (prevent by coadministering with mesna)

40
Q

Interstitial nephritis

A

Methicillin, NSAIDs, furosemide

41
Q

SIADH

A

Carbamazepine, Cyclophosphamide, SSRIs (Can’t Concentrate Serum Sodium)

42
Q

Dry cough

A

ACE inhibitors

43
Q

Pulmonary fibrosis

A

Bleomycin, Amiodarone, Busulfan, Methotrexate (Breathing Air Badly from Medications)

44
Q

Antimuscarinic

A

Atropine, TCAs, H1-blockers, antipsychotics

45
Q

Disulfiram-like reaction

A

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

1st Can Makes Guys Puke

46
Q

Nephrotoxicity/ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin

47
Q

Cytochrome P450 Inducers

A

Chronic alcohol use, St. John’s wort, Phenytoin, Phenobarbital, Nevirapine, Rifampin, Griseofulvin, Carbamazepine (Chronic alcoholics Steal Phen-Phen and Never Refuse Greasy Carbs)

48
Q

Cytochrome P450 Substrates

A

Anti-epileptics, Theophylline, Warfarin, OCPs (Always Think When Outdoors)

49
Q

Cytochrome P450 Inhibitors

A

Acute alcohol abuse, Ritonavir, Amiodarone, Cimetidine, Ketoconazole, Sulfonamides, Isoniazid (INH), Grapefruit juice, Quinidine, Macrolides (except azithromycin) (AAA RACKS IN GQ Magazine)

50
Q

Sulfa drugs

A

Probenecid, Furosemide, Acetazolamide, Celecoxib, Thiazides, Sulfonamide antibiotics, Sulfasalazine, Sulfonylureas (Popular FACTSSS)

51
Q

DRESS syndrome

A

Present with eosinophilia, fever, facial edema, lymphadenopathy, skin rash – Anticonvulsants, allopurinol, sulfonamide, antibiotics

Step 1 First Aid (8 decks)

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