Pharm Side Effects

Question 1

Coronary vasospasm

Answer 1

Cocaine, sumatriptan, ergot alkaloids

Question 2

Cutaneous flushing

Answer 2

Vancomycin, Adenosine, Niacin, Ca channel blockers (VANC)

Question 3

Dilated cardiomyopathy

Answer 3

Anthracyclines (doxorubicin, daunorubicin), prevent with dexrazoxane

Question 4

Torsades de pointes

Answer 4

Class III (sotalol) and class IA (quinidine) antiarrhythmics, macrolide antibiotics, antipsychotics, TCAs

Question 5

Adrenocortical insufficiency

Answer 5

HPA suppression secondary to glucocorticoid withdrawal

Question 6

Hot flashes

Answer 6

Tamoxifen, clomiphene

Question 7

Hyperglycemia

Answer 7

Tacrolimus, Protease inhibitors, Niacin, HCTZ, Corticosteroids (Taking Pills Necessitates Having blood Checked)

Question 8

Hypothyroidism

Answer 8

Lithium, amiodarone, sulfonamides

Question 9

Acute cholestatic hepatitis, jaundice

Answer 9

Erythromycin

Question 10

Diarrhea

Answer 10

Metformin, Erythromycin, Colchicine, Orlistat, Acarbose (Might Excite Colon On Accident)

Question 11

Focal to massive hepatic necrosis

Answer 11

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen (Liver HAVAc)

Question 12

Hepatitis

Answer 12

Rifampin, isoniazid, pyrazinamide, statins, fibrates

Question 13

Pancreatitis

Answer 13

Didanosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (Drugs Causing A violent Abdominal Distress)

Question 14

Pseudomembranous colitis

Answer 14

Clindamycin, ampicillin, cephalosporins – CLAMP your Ass

Question 15

Agranulocytosis

Answer 15

Ganciclovir, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil (Gangs CCCrush Myeloblasts and Promyelocytes)

Question 16

Aplastic anemia

Answer 16

Carbamazepine, Methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil (Can’t Make New Blood Cells Properly)

Question 17

Direct Coombs-positive hemolytic anemia

Answer 17

Methyldopa, penicillin

Question 18

Gray baby syndrome

Answer 18

Chloramphenicol

Question 19

Hemolysis in G6PD deficiency

Answer 19

Isoniazid, Sulfonamids, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin (Hemolysis IS D PAIN)

Question 20

Megaloblastic anemia

Answer 20

Phenytoin, Methotrexate, Sulfa drugs (Having a BLAST with PMS)

Question 21

Thrombocytopenia

Answer 21

Heparin

Question 22

Thrombotic complications

Answer 22

OCPs, hormone replacement therapy

Question 23

Fat redistribution

Answer 23

Protease inhibitors, Glucocorticoids (Fat PIG)

Question 24

Gingival hyperplasia

Answer 24

Phenytoin, Ca channel blockers, cyclosporine

Question 25

Hyperuricemia (gout)

Answer 25

Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine (Painful Tophi and Feet Need Care)

Question 26

Myopathy

Answer 26

Fibrates, niacin, colchicine, hydroxychloroquine, interferon-a, penicillamine, statins, glucocorticoids

Question 27

Osteoporosis

Answer 27

Corticosteroids, heparin, aromatase inhibitors, PPIs

Question 28

Photosensitivity

Answer 28

Sulfonamides, Amiodarone, Tetracyclines, 5-FU (SAT For Photo)

Question 29

Rash (Stevens-Johnson syndrome)

Answer 29

Anti-epileptic drugs (especially lamotrigine), allopurinol, sulfa drugs, penicillin (sulfas, cilins, seizures, and allopurinol)

Question 30

SLE-like syndrome

Answer 30

Sulfa drugs, Hydralazine, Isoniazid, Procainamide, Phenytoin, Etanercept (Having lupus is SHIPP-E) --- Have anti-histone antibodies

Question 31

Teeth discoloration

Answer 31

Tetracyclines

Question 32

Tendonitis, tendon rupture, and cartilage damage

Answer 32

Fluoroquinolones

Question 33

Cinchonism

Answer 33

Quinidine, quinine

Question 34

Parkinson-like syndrome

Answer 34

Antipsychotics, Reserpine, metoclopramide (Cogwheel rigidity of ARM)

Question 35

Seizures

Answer 35

Isoniazid (vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Enflurane (With seizures, I BItE my tongue)

Question 36

Tardive dyskinesia

Answer 36

Antipsychotics, metoclopramide

Question 37

Diabetes insipidus

Answer 37

Lithium, demeclocycline

Question 38

Fanconi syndrome

Answer 38

Expired tetracycline

Question 39

Hemorrhagic cystitis

Answer 39

Cyclophoshpamide, ifosfamide (prevent by coadministering with mesna)

Question 40

Interstitial nephritis

Answer 40

Methicillin, NSAIDs, furosemide

Question 41

SIADH

Answer 41

Carbamazepine, Cyclophosphamide, SSRIs (Can't Concentrate Serum Sodium)

Question 42

Dry cough

Answer 42

ACE inhibitors

Question 43

Pulmonary fibrosis

Answer 43

Bleomycin, Amiodarone, Busulfan, Methotrexate (Breathing Air Badly from Medications)

Question 44

Antimuscarinic

Answer 44

Atropine, TCAs, H1-blockers, antipsychotics

Question 45

Disulfiram-like reaction

Answer 45

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas 1st Can Makes Guys Puke

Question 46

Nephrotoxicity/ototoxicity

Answer 46

Aminoglycosides, vancomycin, loop diuretics, cisplatin

Question 47

Cytochrome P450 Inducers

Answer 47

Chronic alcohol use, St. John's wort, Phenytoin, Phenobarbital, Nevirapine, Rifampin, Griseofulvin, Carbamazepine (Chronic alcoholics Steal Phen-Phen and Never Refuse Greasy Carbs)

Question 48

Cytochrome P450 Substrates

Answer 48

Anti-epileptics, Theophylline, Warfarin, OCPs (Always Think When Outdoors)

Question 49

Cytochrome P450 Inhibitors

Answer 49

Acute alcohol abuse, Ritonavir, Amiodarone, Cimetidine, Ketoconazole, Sulfonamides, Isoniazid (INH), Grapefruit juice, Quinidine, Macrolides (except azithromycin) (AAA RACKS IN GQ Magazine)

Question 50

Sulfa drugs

Answer 50

Probenecid, Furosemide, Acetazolamide, Celecoxib, Thiazides, Sulfonamide antibiotics, Sulfasalazine, Sulfonylureas (Popular FACTSSS)

Question 51

DRESS syndrome

Answer 51

Present with eosinophilia, fever, facial edema, lymphadenopathy, skin rash -- Anticonvulsants, allopurinol, sulfonamide, antibiotics