Pharm quiz 1

Question 1

If you wanted to maximize the bioavailability of a drug when administering it to your patient then you should give the medication by mouth. T/F?

Answer 1

False: oral enteral route must go through first pass Chemically changes the drug to be excreted easily

Question 2

A decreased response to a drug over time and requires a higher dose of that drug to achieve the desired effect describes….

Answer 2

drug tolerance

Question 3

Lipid soluble drugs are:

Answer 3

hydrophobic and lipophilic

Question 4

elderly pt have altered drug disposition because of

Answer 4

a reduced capacity to metabolize drugs

Question 5

The rate and extent to which the active ingredient of an administered drug enters the systemic circulation, reaches the site of action, and is available to produce its effect is known as:

Answer 5

Bioavailability

Question 6

What are some factors that affect drug absorption?

Answer 6

Kidney and liver function, age, disease

Question 7

A medical Doctor is the only person legally allowed to write and give out a prescription.

(t/f)

Answer 7

false

Question 8

what is the most common type of drug receptor?

Answer 8

G-protein coupled receptors

Question 9

Enteral drug administration allows the drug to pass directly into the circulatory system.

T/F?

Answer 9

false

Question 10

what is a drug?

Answer 10

a chemical substance when giving to a living this causes a biological response.

Question 11

What are therapeutics?

Answer 11

the medical use of the drugs

Question 12

what is pharmacology?

Answer 12

the study of how drugs interact with living systems.

Question 13

what is clinical pharmacology:

Answer 13

the study of drugs in humans

Question 14

The knowledge of drug properties, mechanisms of action and anatomy, physiology, and patho apply to……

Answer 14

applies to the study of pharmacology.

Question 15

When a drug binds to a receptor and alters the cell function, this is known as a therapeutic response.

(t/F)?

Answer 15

true

Question 16

what is the additive affect of a drug?

Answer 16

occurs when the combined effect of 2 drugs= to the su of each drug individually

Question 17

The process in which the liver clears a portion of an administered drug before it moves into the general circulation is known as:

Answer 17

first pass effect

Question 18

a partial agonist is best described as an agent that ……

Answer 18

can’t produce a max effect even at high doses

Question 19

Which endeavour is most important for determining the dose-response relationship of a drug?

Answer 19

correct isolation of the pure drug.

Question 20

The official non-proprietary name of a drug is the:

Answer 20

generic name

Question 21

Elimination half-life is the time required to reduce the plasma drug concentration by 50%.

T/F?

Answer 21

True

Question 22

A patient with renal disease exhibits first-order elimination of a drug she is taking. what is first order elimination?

Answer 22

the elimination of the drug is proportional to the plasma concentration and the half-life is constant.

Question 23

what is biotransformation?

Answer 23

metabolism

Question 24

The process of the movement of a drug from the circulatory system across barrier membranes to the site of drug action is known as absorption.

t/f?

Answer 24

false

Question 25

Morphine sulphate tablets are an example of which type of drug preparation?

Answer 25

pharmaceutical formulation

Question 26

The process that involves the movement of drug molecules from the site of administration, across a cell membrane, and into the circulatory system is known as:

Answer 26

absorption

Question 27

the study of the constitutes of natural drugs that are responsible for their effects is known as….

Answer 27

pharmacognosy

Question 28

The primary route of elimination for a drug is through:

Answer 28

urination