Pharm HRT Med Sheet Flashcards

1
Q

Medroxyprogesterone Acetate (MPA) Trade Name

A

Provera

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2
Q

Medroxyprogesterone Acetate (MPA) Category

A

Oral progestogen

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3
Q

Medroxyprogesterone Acetate (MPA) Use

A

HRT

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4
Q

Medroxyprogesterone Acetate (MPA) Usual dose

A

2.5-10 mg PO qday

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5
Q

Medroxyprogesterone Acetate (MPA) AEs

A
  • N/HA
  • wt gain
  • bleeding
  • irritability
  • depression
  • VTE
  • decreased BMD
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6
Q

Conjugated Equine Estrogen (CEE) Trade Name

A

Premarin

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7
Q

Conjugated Equine Estrogen (CEE) Category

A

oral or topical estrogen

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8
Q

Conjugated Equine Estrogen (CEE) Use

A

HRT

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9
Q

Conjugated Equine Estrogen (CEE) Usual Dose

A
  • vaginal cream: 0.5-2 gm/day

- oral estrogen: 0.3-0.625 mg/day

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10
Q

Conjugated Equine Estrogen (CEE) AEs

A
  • N/HA
  • bloating
  • breast tenderness
  • bleeding
  • CHD, VTE
  • stroke
  • breast CA
  • gallbladder dz
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11
Q

Estradiol Transdermal Trade Name

A

Alora
Climara
Estraderm
Vivelle

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12
Q

Estradiol Transdermal Category

A

-transdermal estrogen

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13
Q

Estradiol Transdermal Use

A

HRT

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14
Q

Estradiol Transdermal Usual Dose

A

0.025-0.05 mg changed weekly or twice weekly

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15
Q

Estradiol Transdermal AEs

A
  • N/HA
  • bloating
  • breast tenderness
  • bleeding
  • CHD, VTE
  • stroke
  • breast CA
  • gallbladder dz
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16
Q

Estradiol/Norethindrone Trade Name

A

Activella (oral)

CombiPatch (transdermal)

17
Q

Estradiol/Norethindrone Category

A

oral or transdermal estrogen and progestogen

18
Q

Estradiol/Norethindrone Use

A

HRT

19
Q

Estradiol/Norethindrone Usual Dose

A
  • oral: 1 tablet qday (0.5/0.1 mg - 1/0.5 mg)

derm: 1 patch 2x per week (0.05/0.14 - 0.05/0.25 mg in 24 hours)

20
Q

Estradiol/Norethindrone AEs

A
  • N/HA
  • wt gain
  • bleeding
  • irritability
  • depression
  • VTE
  • decreased BMD
21
Q

All HRT Drug CIs

A
  • hx of VTE/DVT/PE
  • breast CA
  • pregnancy
  • liver dz
  • undiagnosed vaginal bleeding