Pharm HRT Med Sheet Flashcards by Lauren Babcock

Q

Medroxyprogesterone Acetate (MPA) Trade Name

A

Provera

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Q

Medroxyprogesterone Acetate (MPA) Category

A

Oral progestogen

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Q

Medroxyprogesterone Acetate (MPA) Use

A

HRT

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Q

Medroxyprogesterone Acetate (MPA) Usual dose

A

2.5-10 mg PO qday

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Q

Medroxyprogesterone Acetate (MPA) AEs

A

N/HA
wt gain
bleeding
irritability
depression
VTE
decreased BMD

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Q

Conjugated Equine Estrogen (CEE) Trade Name

A

Premarin

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Q

Conjugated Equine Estrogen (CEE) Category

A

oral or topical estrogen

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Q

Conjugated Equine Estrogen (CEE) Use

A

HRT

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Q

Conjugated Equine Estrogen (CEE) Usual Dose

A

vaginal cream: 0.5-2 gm/day

- oral estrogen: 0.3-0.625 mg/day

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Q

Conjugated Equine Estrogen (CEE) AEs

A

N/HA
bloating
breast tenderness
bleeding
CHD, VTE
stroke
breast CA
gallbladder dz

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Q

Estradiol Transdermal Trade Name

A

Alora
Climara
Estraderm
Vivelle

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Q

Estradiol Transdermal Category

A

-transdermal estrogen

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Q

Estradiol Transdermal Use

A

HRT

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Q

Estradiol Transdermal Usual Dose

A

0.025-0.05 mg changed weekly or twice weekly

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Q

Estradiol Transdermal AEs

A

N/HA
bloating
breast tenderness
bleeding
CHD, VTE
stroke
breast CA
gallbladder dz

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Q

Estradiol/Norethindrone Trade Name

A

Activella (oral)

CombiPatch (transdermal)

Q

Estradiol/Norethindrone Category

A

oral or transdermal estrogen and progestogen

Q

Estradiol/Norethindrone Use

A

HRT

Q

Estradiol/Norethindrone Usual Dose

A

oral: 1 tablet qday (0.5/0.1 mg - 1/0.5 mg)

derm: 1 patch 2x per week (0.05/0.14 - 0.05/0.25 mg in 24 hours)

Q

Estradiol/Norethindrone AEs

A

N/HA
wt gain
bleeding
irritability
depression
VTE
decreased BMD

Q

All HRT Drug CIs

A

hx of VTE/DVT/PE
breast CA
pregnancy
liver dz
undiagnosed vaginal bleeding