Pharm Final: Respiratory

Question 1

What meds should be used for exercise induced asthma?

Answer 1

Long acting beta-blockers should be used in combination with rapid-acting agonist
-combined preparations (glucocorticoid + bronchodilator)

-Rescue inhalers as backup

Question 2

Bronchodilators
Use:
Side Effects:
Mechanism of Action:

Answer 2

Beta-Adrenergic Agonists: Act on B-2 receptors on respiratory smooth muscle cells to cause relaxation and bronchodilation (ASTHMA)

Anti-Cholinergic: Block muscarinic cholinergic receptors to prevent acetylcholine-induced bronchoconstriction; inhaled treatment (COPD, CHRONIC BRONCHITIS)

Xanthine Derivatives: CNS stimulant for reversible airway obstruction. Works on smooth muscle cells to bronchodilate, but also has anti-inflammatory effect by inhibiting phosphodiesterase enzyme (BRONCHITIS, EMPHAZEMA - reversible airway obstruction)

Question 3

What medications are for pulmonary Obstruction (vs congestion)? (6)

Answer 3

1. Bronchodilators: Xanthine Derivatives
2. Bronchodilators: Anti-cholinergics
3. Bronchodilators: Beta Adrenergic Agonists
4. Anti-inflammatory: leukotriene inhibitors
5. Anti-inflammatory: cromones
6. Anti-inflammatory: glucocorticoids

Question 4

What medications are for pulmonary Congestion (vs obstruction)? (4)

Answer 4

1. Antitussives
2. Decongestants
3. Expectorants and Mucolyticis
4. Antihistamines