Pharm Exam 1 Final Flashcards

1
Q

Where is DEA number found on a prescription?

A

The closing

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2
Q

What is the purpose of a black box warning?

A

To draw attention to being potentially fatal.

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3
Q

Schedule 3 drugs can be what?

A

Telephoned in and refills are no more than 5 times in a 6 month period.

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4
Q

Schedule 2 drugs need

A

A written prescription

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5
Q

A drug can have only___ generic name and _________ trade names.

A

1 generic

Several trade

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6
Q

Herbs can cause

A

Adverse effects

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7
Q

A drug biologically active can do what?

A

Modify cellular function

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8
Q

A dose response curve for a more efficacious drug will have what?

A

Greater curve height

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9
Q

Therapeutic index ratio

A

Median lethal dose to median effective dose

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10
Q

Drugs competing for the same receptor

A

Drug with stronger affinity for the receptor will bind to more receptor than drug with weaker affinity.

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11
Q

A drug that has an affinity for a receptor and produces no effect?

A

Competitive antagonist

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12
Q

A substance is transported against concentration gradient is know as what?

A

Active transport

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13
Q

Half-life is related to what?

A

Duration

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14
Q

Where is the most common site for bio transformation?

A

Liver

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15
Q

A drug with zero-order elimination kinetics means what?

A

Constant amount of the drug is eliminated and is retained in the body.

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16
Q

Patients perception that a pill without active ingredient is having a pharmacological effect is what?

A

Placebo Effect

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17
Q

Hypersensitivity reaction that causes antibody antigen deposition?

A

Type 3

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18
Q

True or False? Drug A and drug B have same ED 50, Drug B has a wider TI; therefore drug A has a greater LD 50 than B.

A

First statement True

Second statement False

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19
Q

SLUD is the adverse reactions for

A

cholinergic

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20
Q

What does the S stand for in SLUD

A

Salivation

21
Q

Which statement is most correct concerning the sympathetic autonomic nervous system (SANS)?
A) Multiple preganglionic fibers synapse with a single postsynaptic neuron to produce a localized effect.
B) A single preganglionic fiber often synapses with numerous postganglionic neurons to produce a diffuse effect.
C) Multiple preganglionic fibers synapse with a multiple postsynaptic neurons to produce a localized effect.
D) A single preganglionic fiber often synapses with single postganglionic neurons to produce a diffuse effect.

A

B

22
Q

What is the preganglionic neurotransmitter of the parasympathetic nervous system?

A

Acetylcholine

23
Q

Which naturally occurring cholinergic agents is given to stimulate saliva flow?

A

pilocarpine

24
Q

Which statements are true about the preganglionic fibers of the PANS?
A.) Preganglionic fibers are relatively long and extend near to or into the innervated organ.
B.) A low ratio of synaptic connections between preganglionic and postganglionic neurons usually exists, leading to a discrete or more localized response when the PANS is stimulated.
C.) Postganglionic fibers are usually short and terminate on the innervated tissue.
D.) Nerve distribution is complex for the third, seventh, and ninth cranial nerve and is relatively simple for the tenth or vagus nerve.
E.) All of these statements are true. Incorrect
F.) Only a, b, and c are true.

A

F

25
Q

What schedule of drug is most abusive

A

I

26
Q

This schedule of drugs may not be refilled more than five times in 6 month period

A

Schedule III-IV

27
Q

A biologically active substance that can modify cellular function

A

Drug

28
Q

Undesirable response to drug; potentially harmful; occurs at usual therapeutic doses

A

Adverse reaction

29
Q

A drug may have more than one generic name, but only one trade or propriety name

A

Both statements are false

30
Q

Ganglions of parasympathetic autonomic system

A

long preganglionic neurons to short postganglionic

31
Q

These are associated with PANS

A

Cranial nerves and sacral segments of spinal cord

32
Q

When a higher dose of a drug causes he same effect

A

Drug tolerance

33
Q

The type of administration of a drug effects the onset and duration of the response

A

TRUE

34
Q

An effect of a drug that is not predictable or dose related

A

Drug allergy

35
Q

A non therapeutic action

A

IS NOT FOR TARGET TISSUES

36
Q

When is a fetus most at risk of the mom is taking meds

A

Before pregnancy status is known

37
Q

Life threatening hypersensitivity

A

Type 1

38
Q

Immune complex sensitivity

A

Type 3

39
Q

Delayed hypersensitivity

A

4

40
Q

A dose of meds hat kills 50 % of the animals

A

Lethal dose 50

LD50

41
Q

The LD50 of drug A and drug B is the same but the therapeutic index is wider and that makes drug A toxic dose greater than drug B

A

The first statement is true the second statement is false

42
Q

If a pt has a suspected adverse reaction what is the first thing you should do

A

Ask what meds they’re taking

43
Q

An allergy and a side effect are examples of a dose related response

A

FALSE

44
Q

Tetracycline NSAIDS and benzocaine are safe while pregnant

A

FALSE

45
Q

The greater the therapeutic index the greater the toxicity

A

FALSE

46
Q

The autonomic nervous system functions as ____ for bodily functions

A

Autonomic modulating

47
Q

A reaction that is neither the drug’s side effect nor an allergic reaction

A

Idiosyncratic reaction

48
Q

Which does not raise the pain threshold?

A

Prostaglandins