Pharm comprehensive Flashcards

1
Q

Per os

A

by mouth

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2
Q

the degree to which a drug is absorbed and reaches general circulation is called

A

bioavailability

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3
Q

Passive transport and phagocytosis require energy

A

true

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4
Q

increased blood supply to tissues can increase drug absorption

A

true

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5
Q

lipophilic mans water loving

A

false

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6
Q

Facilitates diffusion does not require energy

A

true

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7
Q

The status of the GI tract can affect absorption of drugs.

A

True

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8
Q

Drugs can only pass through a cell membrane if they are

A

non-ionized

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9
Q

Drugs bound to proteins are

A

inactive

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10
Q

This protects a fetus from some drugs that can be toxic.

A

placental barrier

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11
Q

Once a drug has been bio transformed, it is called a?

A

metabolite

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12
Q

This species has a deficient in glucuronic acid

A

Cats

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13
Q

What is the functional part of the kidneys?

A

nephron

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14
Q

Tubular secretion does not depend on the concentration gradient

A

true

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15
Q

_____ are quantities of drugs that remain in animal products when consumed

A

Drug residues

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16
Q

This is the term the describes how well a drug works

A

efficacy

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17
Q

Naloxone will knock opioids off the receptor they bind with. This is known as?

A

antagonist

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18
Q

Morphine will bind to MU receptors in the brain very strongly. Morphine is known as a MU

A

agonist

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19
Q

The safer the drug, the lower the therapeutic index

A

false

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20
Q

An adverse drug event is due to inherent properties of the drug itself

A

false

21
Q

Drug interactions can be detrimental or beneficial

A

true

22
Q

Why are over the counter drugs sold without a prescription?

A

they have a wide range of safety. It is difficult to use them in harmful ways.

23
Q

Prescription drugs are approved by the

A

FDA

24
Q

What is a proprietary name?

A

A name given to the drug by the manufacturer

25
Q

The trade name and generic name are the same thing.

A

false

26
Q

Because there is so much information, many drugs manufacturers include

A

package inserts

27
Q

The animal medicinal drug use clarification act regulates extra label drug use. This was passed in?

A

1994

28
Q

The act of diluting or mixing existing medications is known as?

A

compounding

29
Q

What the drug does to a drug is called

A

pharmacokinetics

30
Q

The sequence of pharmacokinetics is

A

Absorption, distribution, biotransformation, excretion

31
Q

___ is the range of drug levels in the blood of a patient in which a drug has the desired effect

A

Therapeutic range

32
Q

Therapeutic window is

A

the range of dosage of a drug or of its concentration in a bodily system that provides safe effectiveness

33
Q

Narrow therapeutic range means

A

This drug can be overdosed easily

34
Q

The rate at which a drug will remain at the same levels in the body

A

Steady state

35
Q

Which means to give an injection into a muscle

A

Intramuscular (IM)

36
Q

If you give an injection just under the skin, this is known as

A

SQ/subcutaneous

37
Q

This is the route of administration of drugs that achieves the quickest blood levels

A

IV

38
Q

You have been instructed to give an injection in the saphenous vein of a dog. Where is this vein?

A

rear leg

39
Q

IM injections have a slower onset but longer duration

A

True

40
Q

Where are the epaxial muscles

A

Lower back

41
Q

This is the movement of drug molecules from the site of administration to systemic throughout the day

A

absorption

42
Q

Bioavailability will vary based on drug form, administration route and other factors

A

true

43
Q

Passive absorption

A

Drug movement from a high to low concentration

44
Q

Active transport

A

a cell has to spend energy to move molecules from a high to low concentration

45
Q

pinocytosis

A

when a cell engulfs a drug molecule-essentially a cell eats it.

46
Q

Factors that effect drug absorption

A

Mechanism of absorption
Blood supply to the area
Solubility of the drug

47
Q

What is an extra label use

A

When you are using that drug for an animal that is not on the manufactures label. like giving a dog a medication that is meant for cats.

48
Q

Why are generic drugs cheaper than brand name?

A

The brand name does all the testing and research

49
Q

What must be established in order for a veterinarian to prescribe a medication to an animal?

A

VCPR