Pharm comprehensive Flashcards
Per os
by mouth
the degree to which a drug is absorbed and reaches general circulation is called
bioavailability
Passive transport and phagocytosis require energy
true
increased blood supply to tissues can increase drug absorption
true
lipophilic mans water loving
false
Facilitates diffusion does not require energy
true
The status of the GI tract can affect absorption of drugs.
True
Drugs can only pass through a cell membrane if they are
non-ionized
Drugs bound to proteins are
inactive
This protects a fetus from some drugs that can be toxic.
placental barrier
Once a drug has been bio transformed, it is called a?
metabolite
This species has a deficient in glucuronic acid
Cats
What is the functional part of the kidneys?
nephron
Tubular secretion does not depend on the concentration gradient
true
_____ are quantities of drugs that remain in animal products when consumed
Drug residues
This is the term the describes how well a drug works
efficacy
Naloxone will knock opioids off the receptor they bind with. This is known as?
antagonist
Morphine will bind to MU receptors in the brain very strongly. Morphine is known as a MU
agonist
The safer the drug, the lower the therapeutic index
false