Pharm: Cholinergics Flashcards
1
Q
What do cholinergics do?
A
increase parasympathetic innervation
2
Q
What do anticholinergics do?
A
block parasympathetic innervation, eg atropine
3
Q
bethanechol
A
a MAChR specific cholinergic, used postoperatively to counteract urine and GI retention
4
Q
what class of anticholinergics does atropine belong to?
A
tertiary amines, it can cross the BB barrier
5
Q
ipratropium, tiotropium
A
quaternary amines, don’t cross BB barrier and are used prophylactically for asthma
6
Q
hexamethonium?
A
it acts post-synaptically at the autonomic ganglia on neuronal NAChR’s to block ACh release at end target; ultimately blocks parasympathetic innervation