Pharm: Cholinergics Flashcards

1
Q

What do cholinergics do?

A

increase parasympathetic innervation

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2
Q

What do anticholinergics do?

A

block parasympathetic innervation, eg atropine

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3
Q

bethanechol

A

a MAChR specific cholinergic, used postoperatively to counteract urine and GI retention

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4
Q

what class of anticholinergics does atropine belong to?

A

tertiary amines, it can cross the BB barrier

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5
Q

ipratropium, tiotropium

A

quaternary amines, don’t cross BB barrier and are used prophylactically for asthma

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6
Q

hexamethonium?

A

it acts post-synaptically at the autonomic ganglia on neuronal NAChR’s to block ACh release at end target; ultimately blocks parasympathetic innervation

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