Pharm Chapt 14-18 Flashcards

1
Q

Chronic, recurrent seizures activity

A

Epilepsy

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2
Q

Episode of abnormal electrical activity in the brain

A

Seizure

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3
Q

Severe seizure w/ spasmodic contractions of voluntary muscles

A

Convolsions

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4
Q

Epilepsy with no identifiable cause

A

Primary or idiopathic epilepsy

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5
Q

Epilepsy with distinct cause

A

Secondary or Symptomatic epilepsy

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6
Q

Caused by fever in children 6mo-5yrs

A

Febrile seizures

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7
Q

Generalized onset seizure (in gray matter bilateral hemispheres)

A

Grand Mal

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8
Q

Begin w/ muscular contractions through the body

A

Tonic-clonic seizure

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9
Q

Originate in one lobe of brain

A

Partial onset

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10
Q

multiple, with no recovery between, Life-threatening

A

Status epilepticus

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11
Q

Before multiple drug therapy

A

single drug therapy must fail

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12
Q

Contraindications

A

known drug allergy, pregnancy

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13
Q

Anti-epileptic drugs have

A

black box warnings and narrow therapeutic range

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14
Q

Characterized by a blank stare, last a few seconds

A

absence seizures

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15
Q

Chronic, degeneration of dopamine producing neurons

A

Parkinson’s disease

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16
Q

Precursor to epinephrine and other neurotransmittors

A

Dopamine

17
Q

Inhibitory neurotransmittor

A

Dopamine

18
Q

Excitatory neurotransmittor

A

acetylcholine

19
Q

Classic symptoms: TRAP

A

Tremor, Rigidity, Akinesia, Postural instability

20
Q

Irregular, spasmodic, involuntary movements

A

Chorea

21
Q

Abnormal muscle tone

A

Dystonia

22
Q

Emotional disorders characterized by mood changes

A

Affective disorder

23
Q

first-line drug therapy for both acute and chronic anxiety disorders

A

Benzodiazepines

24
Q

increases the action of gamma-aminobutyric acid (GABA), and inhibitory Neurotransmitter

A

Benzodiazepines

25
Q

Do not use MOA inhibitors with

A

Meperidine/CNS depressants

26
Q

Schizophrenia, mania, depression

A

Dopamine

27
Q

Mania, anxiety, depression

A

Norepinephrine

28
Q

Anxiety, depression

A

Serotonin

29
Q

Depression, weight gain

A

Histamine

30
Q

Mania, anxiety, schizophrenia

A

GABA

31
Q

Assess for suicidal thoughts, dont take with NSAIDS, loss of libido, Serotonin Syndrome

A

SSRI’s

32
Q

Many drug and food interactions (wine, cheese)

A

MAOI’s

33
Q

Cardiac concerns associated with

A

TCA’s

34
Q

Typical Antipsychotics

A

1st generation (improves positive symptoms)

35
Q

Atypical Antipsychotics

A

2nd Generation (improve + and - symptoms)

36
Q

1-5 day peak, last 5-7 days

A

Opioid withdrawl

37
Q

1-3 day peak, lasts 5-7 days

A

Stimulant withdrawl

38
Q

Taper drug over 10-14 days

A

Benzos/Barbs