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Paige - ID Module! > PHARM BLESSINGS :) > Flashcards

PHARM BLESSINGS :) Flashcards

1
Q

yaaaaaaaaaaaaaaaaaasssssssss

phhhhaaaaaaaarrrrrrrmmmmmm

ayyyyyyoooooooooooooooooo

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2
Q

Which 2 drugs, when prescribed together, can cause depression?

A

Ribavarin [Rebetol] + PEG-Interferon [Pegasys]

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3
Q

What percentage of people on Ribavarin [Rebetol] + PEG-Interferon [Pegasys] develop depression?

A

80%

(know this!)

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4
Q

What other side effects are seen with PEG-interferon [pegasys]

A

flu-like symptoms

(fever, chills, body aches)

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5
Q

can you use PEG-interferon [pegasys] for:

Hep B?

Hep C?

HIV?

A

B: yes

c: yes

HIV: no

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6
Q

can you use lamivudine [epivir] for:

hep b?

hep c?

hiv?

A

b: yes
c: no!
hiv: yes

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7
Q

which 2 meds are most commonly used with TB?

A

isoniazid and rifampin [rifadin]

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8
Q

By law, how should meds be given for TB?

A

direct observation therapy (DOT) to make sure they’re taking all their meds

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9
Q

what type of drug class can be used in TB?

A

mycobacterials

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10
Q

An infectious disease walks into a bar. The bartender says, “Oh, we don’t serve infectious diseases here.” What does the infectious disease say?

A

“well, you’re not a very good host.”

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11
Q

which drug can’t be used as sole therapy in TB?

why not?

A

rifampin [rifadin]

resistance builds quickly

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12
Q

what is the major side effect of isoniazid?

A

hepatitis

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13
Q

what is the most common side effect of rifampin [rifadin]

A

red/orange/yellow staining

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14
Q

which drug can cause s/e of anxiety, agitation, dizziness, and insomnia?

A

amantadine [symmetrel]

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15
Q

by how many days does tamiflu lessen the course of the flu?

A

less than one day

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16
Q

how is the drug zanamivir [relenza] administered

A

inhalation

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17
Q

what do you call a tv show where everyone compares who has the worst infectious disease?

A

deadliest catch

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18
Q

in which patients is zanamivir [relenza] contraindicated?

A

those with pulm diseases

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19
Q

is zanamivir [relenza] effective against both influenza A/B?

A

yes

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20
Q

does amantadine cover both influenza A/B?

A

only covers A

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21
Q

does tamiflu cover both influenza A and B?

A

yes

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22
Q

in the elderly, what do you check before prescribing influenza drugs?

A

eGFR

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23
Q

how do you treat any tick-borne disease?

A

doxycycline

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24
Q

what if a person comes in with a tick bite and is scared but doesn’t have a rash?

A

tell them to suck it up
but you can also give them a 1-time dose of doxycycline

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25
Q

is it necessary to test for lyme disease? why or why not?

A

not necessary - a lot of false positives. only order it if it will actually guide your tx

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26
Q

what tests diagnose lyme disease?

A

pcr and western blot

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27
Q

what is the most common symptom of lyme disease?

A

it turns you lime green

(*disclaimer: in case anyone is actually confused by this card, that’s not true at all)

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28
Q

when does a patient with lyme disease develop erythema migrans (bullseye rash over entire body)?

A

after 4-8 weeks

so AFTER they turn lime green

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29
Q

how many patients do not get a bullseye rash with lyme disease?

A

20%

30
Q

at what egfr do you decrease acyclovir?

A

10-25

then again at < 10

31
Q

can you give a CKD patient valcyclovir for shingles?

A

it’s not really effective because not magical like acyclovir, and also it’s a

prodrug

32
Q

what is a major s/e of acyclovir and valcyclovir in high doses?

A

you turn lime green

just kidding, seizures

33
Q

how do you treat malaria?

A

chloroquine sulfate [aralen]

34
Q

what is the name of the *new* flu vaccine that is not on our drug table?

A

irrelevant

but in case it’s relevent it’s called trivalent

35
Q

what do you call a female salmon?

A

salmonella

36
Q

what is the most common malaria species?

A

falciparum

37
Q

how do you treat head lice?

A

permethrin [nix]

38
Q

is nitrofurantoin [macrobid] safe in pregnant women?

A

yes

39
Q

what does pregnancy put you at a HUGE risk for?

A

someday having teenagers

40
Q

no but for real, what does pregnancy put you at a huge risk for?

A

turning lime green

41
Q

is nitrofurantoin [macrobid] metabolized and excreted quickly or slowly?

A

very quickly!!!!*

as quick as bunnies

42
Q

does nitrofurantoin [macrobid] have lots or little of systemic absorption?

A

just a wee

43
Q

so we’re talking about nitrofurantoin [macrobid] and using it in pregnancy but what do we use it to treat? (from the last module)

A

UTIs

(if you got this wrong: seriously, come on guys, it was less than a week ago)

(just kidding, just keep on being you)

44
Q

during what phases of pregnancy should you not use nitrofurantoin [macrobid]

A

during 1st trimester

before giving birth

during the time that they turn lime green

45
Q

in a CKD patient, do you have to adjust the dose of nitrofurantoin [macrobid]?

A

yes

46
Q

are you SUPER sick of talking about nitrofurantoin [macrobid]?

A

YES ME TOO MOVING ON

47
Q

what is a big side effect of nitrofurantoin [macrobid], especially those with pulmonary issues?

A

pulmonary fibrosis

48
Q

a person comes back from camping, has diarrhea, is lime green, and has been drinking untreated water from the wild wild wilderness where the wild things are. what does he have?

A

traveler’s diarrhea

giardia

they don’t know

idk

49
Q

how do you treat giardia?

A

metronidazole [flagyl]

50
Q

what is praziquantel [bitricide] used to treat?

A

anti-helminth medication

treats schistosomyoniasisisisisiss

another one of those f*cking words i just can’t hang with

51
Q

what is the s/e of metronidazole [flagyl] when you mix it with alcohol

A

disulfram-like effects

like PUKE PUKE PUKE

52
Q

the infectious disease was kind of low on money, so what did she have to do for work to support her family?

A

she became a strepper

(I am sorry that you had to read this awful joke)

53
Q

what does iodoquinol [yodoxin] treat?

A

intestinal amoeba infections

54
Q

what can iodoquinol [yodoxin] interfere with?

A

iodine metabolism

55
Q

what do you give if you want to prevent a person from going from latent TB to the real shiz?

A

isoniazid

56
Q

what level will isoniazid mess up?

A

B6

57
Q

these next ones are kind of loaded

A

but you’re pretty smart so I’m sure you’ll *catch* on……… just like an infectious disease!

also if you know the drug type, you pretty much know the MOA!

58
Q

are my jokes getting worse?

A

yes

i know

i’ll work on it for next semester i promise

59
Q

what is ribavarin [rebetol] for and what is its MOA?

A

anti Hep-C

inhibits protein synthesis

used in adjunct with PEG-interferon

60
Q

what type of drug is lamivudine [epivir]

what is its MOA

and what is it for?

A

antiretroviral drug - NRTI

inhibits viral RNA to DNA transcription

for HIV, HBV

61
Q

what type of drug is delaviridine [rescriptor]

what is its MOA

what is it for

A

antiretroviral: NNRTI

Non-Nucleoside Reverse Transcriptase Inhibitor

for HIV

62
Q

what type of drug is darunivir [preziesta]

what’s the MOA

what is it for

A

antiretroviral: PI

binds to active site of HIV protease

HIV

63
Q

what type of drug is enfuvirtide [fuzeon]

what is its MOA

what is it for

A

antiretroviral: fusion inhibitors

inhibits fusion of virus with host cell membrane

HIV

64
Q

what type of drug is maraviroc [selzentry]

what is its MOA

what is it for

A

antiretroviral: CCR5 inhibitor

binds to CCR5 to inhibit HIV attachment

65
Q

what type of drug is raltegravir [insentress]

A

antiretroviral: integrase inhibitor

inhibits HIV integrase to prevent viral DNA insertion

HIV

66
Q

what type of drug is lamivudine [epivir]

what’s the MOA

what’s it for

A

Anti-hep B drug

inhibits reverse transcriptase

HBV, HIV

67
Q

PEGylated-interferon alpha A2 [pegasys]

A

Antihepatitis B or C drug

it like stops everything

HBV, HCV

68
Q

what type of drug is Ribavirin [Rebetron]

what does it treat

A

antihepatitis C drug

hcv, rsv

used with PEG-Interferon

69
Q

there are 2 more antiviral drugs

i’m not doing them

there’s like a 0.5% chance we’ll even be tested on them

A

keep calm

pharm on

70
Q

by the way, are you still listening to matchbox 20 from slide one?

A

regardless of whether you say yes or no,

good for you

Paige - ID Module! (7 decks)

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