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Pharm Flashcards

1
Q

HER2/neu+ breast cancer

A

Trastuzumab

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2
Q

Buerger disease (vasculitis)

A

Smoking cessation

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3
Q

Ia antiarrhythmic

A

quinidine, procainamide, disopyramide

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4
Q

Tourette

A

Antipsychotics, tetrabenazine

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5
Q

Ribavirin MOA

A

inhibit duplication of viral genetic material

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6
Q

Breast cancer in postmenopausal women

A

Anastrozole

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7
Q

PDA

A

Close with indomethacin. Keep open with PGE

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8
Q

Treatment for Torsades

A

Magnesium sulfate

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9
Q

Chlamydia

A

Doxy+ceftriaxone

Erythromycin eye drops

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10
Q

Schizophrenia

A

Atypical antipsych for pos and neg sym. Typical just for pos

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11
Q

Erectile dysfunc

A

Sildenafil, tadalafil, vardenafil

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12
Q

Clostridium botulinum and tetani

A

Antitoxin

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13
Q

SIADH

A

Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

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14
Q

Osteoporosis

A

Calcium, vit D as prophylaxis

Bisphosphonates, PTH analogs, SERMs, calcitonin, deosumab

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15
Q

Meds that incr risk for osteoporosis

A

antiepileptics, aromatase inhibs, GnRH agonists, PPIs, glucocorticoids

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16
Q

Ulcerative colitis

A

5-ASA preps like mesalamine, 6-mercaptopurine, infliximab, colectomy

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17
Q

Prolactinoma

A

Cabergoline/bromocriptine (dopamine agonists)

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18
Q

Pheochromocytoma

A

Alpha-antags like phenoxybenzamine

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19
Q

Temporal arteritis

A

High dose steroids

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20
Q

Pulm arterial hypertension

A

Sildenafil, bosentan, epoprostenol

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21
Q

Cyclophosphamide-induced hem cystitis

A

Mesna

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22
Q

Crohn

A

Corticosteroids, infliximab, azathriprine

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23
Q

PTSD

A

SSRI, venlafaxine

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24
Q

Acute gout

A

NSAIDs, colchicine, glucocorticoids

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25
Q

GAD

A

SSRI, SNRI

Buspirone is second line

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26
Q

Drugs for chemo-induced nausea

A

Dopamine and serotonin recep antags ie prochlorperazine, metoclopramide, ondansetron

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27
Q

Sickle cell

A

Hydroxyurea (incr HbS)

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28
Q

Candida

A

topical azoles, nystatin, fluconazole, caspofungin, amph B

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29
Q

Tonic-clonic seizures

A

Levetiracetam, phenytoin, valproate, carbamazepine

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30
Q

K+ sparing diuretics

A

Spironolactone, amiloride, triamterene

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31
Q

Warfarin reversal

A

Fresh frozen plasma (acute), vit k (non-acute)

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32
Q

Drugs for motion sickness

A

M1 and H1 antags

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33
Q

Neural tube defect prevention

A

Prenatal folic acid

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34
Q

Prostate adenocarcinoma/uterine fibroids

A

Leuprolide, continuous GnRH

Flutamide just for prostate

35
Q

Social anxiety disorder

A

SSRI, velafaxine

Performance only: propanolol, benzo

36
Q

Bipolar

A

Lithium, valproic acid, carbamazepine, lamotrigine, atypical antipsychotics

37
Q

Anorexia

A

Nutrition, psychotherapy, mirtazapine

38
Q

Acute promyelocytic leukemia

A

All-trans retinoic acid

39
Q

Migraine

A

Abortive: triptans, NSAID
Prophylaxis: propanolol, topiramate, CCBs, amitriptyline

40
Q

Medical abortion

A

Mifepristone

41
Q

Schizophrenia

A

Atypical antipsychotics

42
Q

Osteomalacia/rickets

43
Q

Streptococcus bovis

A

Penicillin; Eval for colon cancer

44
Q

Hyperaldosteronism

A

Spironolactone

45
Q

Toxo gondii

A

Sulfadiazine and pyrimethamine

46
Q

–cept

A

receptor molecule

47
Q

Chronic gout

A

Allopurinol, febuxostat (XO inhibs), pegloticase, probenecid

48
Q

Hypertriglyceridemia

49
Q

BPH

A

alpha-1-antags (zosin), 5alpha reductase inhibs, PDE-5 inhibs

50
Q

Pseudomonas

A

Antipseud penicillins, aminoglycosides, carbapenems

51
Q

Ic antiarrhythmics

A

propafenone, flecainide

52
Q

C diff

A

Metronidazole or oral vanc

53
Q

Amantadine MOA

A

Impair uncoating of influenza A when it’s endocytosed

54
Q

Panic disorder

A

SSRI, venlafaxine, benzo

55
Q

CMV

A

Ganciclovir, foscarnet, cidofovir

56
Q

Anticoag during pregnancy

57
Q

Malaria

A

chloroquine, mefloquine, atovaquone/proguanil (blood schizont), primaquine (liver hypnozoite)

58
Q

Drug-induced long QT

A

antiArrhythmics (Ia, III), antiBiotics (macrolide), antiCychotics (haloperidol), antiDepressants (TCAs), antiEmetics (ondansetron)

59
Q

Cryptococcus neoformans

A

Fluconazole

60
Q

MS

A

Disease modifying: beta-interferon, natalizumab

IV steroids for acute flares

61
Q

Drugs that improve long term survival in HF

A

beta blockers, ACE-Is, ARBs, aldosterone antags

62
Q

heparin reversal

A

Protamine sulfate

63
Q

Triptan MOA

A

Serotonin receptor agonist

64
Q

Infertility

A

Leuprolide, GnRH, clomiphene

65
Q

CML

66
Q

class III antiarrhythmics

A

amiodarone, ibutilide, dofetilide, sotalol

67
Q

ethylene glycol/methanol intox

A

Fomepizole (alc dehydrogenase inhib)

68
Q

DKA

A

Fluids, insulin, K+

69
Q

ER+ breast cancer

70
Q

Myasthenia gravis

A

Acetylcholinesterase inhib (pyridostigmine, physiostigmine etc) & selective muscarinic antagonist (glycopyrrolate, hyoycyamine, propantheline) to reduce SEs

71
Q

H pylori infection

A

PPI, antibiotic (tetracycline, metronidazole), bismuth subsalicylate

72
Q

OCD

A

SSRI, venlafaxine, clomipramine

73
Q

Alcohol withdrawal

A

Long-acting benzos (chlordiazepoxide, lorazepam, diaxepam)

74
Q

Granulomatosis with polyangitis (Wegener)

A

Cyclophosphamide, corticosteroids

75
Q

–nib

A

kinase inhibitor

76
Q

UTI prophylaxis

77
Q

Ib antiarrhythmics

A

lidocaine, mexilientine, (phenytoin)

78
Q

Kawasaki

A

IVIG, high dose aspirin

79
Q

Trigeminal neuralgia

A

Carbamazepine

80
Q

Malignant hyperthermia

A

Dantrolene

81
Q

Chronic hep B or C

A

IFN-gamma

Ribavirin, semiprevir, sofosbuvir (for C)

82
Q

Bulimia

83
Q

Arrhythmia in damaged cardiac tissue

A

IB antiarrhythmics: lidocaine, mexiletine

84
Q

Diabetes insipidus

A

Desmopressin, hydrochlorithiazide, indomethacin, amiloride

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