Pharm Flashcards

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1
Q

What are the 1st gen (or typical or neuroleptics) antipsychotics

A
  • Chlorpromazine
  • Fluphenazine
  • haloperidol
  • perphenazine
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2
Q

What are the second-gen (or atypical) antipsychotics?

A
  • Aripiprazole
  • Asenapine
  • clozapine
  • iloperidone
  • lurasidone
  • Olanzapine
  • Quetiapine
  • risperidone
  • ziprasidone
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3
Q

What do first gen antipsychotics antagonize?

A

Dopamine, mainly D2

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4
Q

What do second gen antipsychotics antagonize

A
  • 5-HT2

- Also dopamine (D4>D2)

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5
Q

What drugs can be used for the akathisia side effect of high potency anti-psychotics

A

-Benzos and beta-blockers

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6
Q

What are the weight neutral 2nd gen anti-psychotics that can be switched to if metabolic syndrome occurs

A
  • aripiprazole

- ziproasidone

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7
Q

Treatment of Huntington’s Disease

A

-symptom-directed therapy, with tetrabenazine or atypical antipsychotics

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8
Q

First line treatment for Tourette’s disorder

A
  • Alpha-2 agonist (guanfacine)

- Clonidine is more sedating

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