Pharm Flashcards
1
Q
What are the 1st gen (or typical or neuroleptics) antipsychotics
A
- Chlorpromazine
- Fluphenazine
- haloperidol
- perphenazine
2
Q
What are the second-gen (or atypical) antipsychotics?
A
- Aripiprazole
- Asenapine
- clozapine
- iloperidone
- lurasidone
- Olanzapine
- Quetiapine
- risperidone
- ziprasidone
3
Q
What do first gen antipsychotics antagonize?
A
Dopamine, mainly D2
4
Q
What do second gen antipsychotics antagonize
A
- 5-HT2
- Also dopamine (D4>D2)
5
Q
What drugs can be used for the akathisia side effect of high potency anti-psychotics
A
-Benzos and beta-blockers
6
Q
What are the weight neutral 2nd gen anti-psychotics that can be switched to if metabolic syndrome occurs
A
- aripiprazole
- ziproasidone
7
Q
Treatment of Huntington’s Disease
A
-symptom-directed therapy, with tetrabenazine or atypical antipsychotics
8
Q
First line treatment for Tourette’s disorder
A
- Alpha-2 agonist (guanfacine)
- Clonidine is more sedating