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Boards Review > Pharm > Flashcards

Pharm Flashcards

1
Q

Which oral medication has the most potential to cause a serious interaction with Amiodarone?

A

Warfarin

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2
Q

What is Warfarin?

A

Anti-coagulant

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3
Q

What is Amiodarone for?

A

Antiarrhythmic drug

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4
Q

Why shouldn’t Amaiodarone and Warfarin be taken concurrently?

A

Enhances Warfarin’s MOA

-may result in increased clotting times and prolonged bleeding

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5
Q

What demographic is most likely to be a steroid responder?

A

Children, especially those under 10

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6
Q

What steroid base is used to minimize the chances of a steroid induced IOP increase?

A

Ester based

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7
Q

What is Vicodin composed of?

A

Acetaminophen and hydrocodone

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8
Q

Ad DFE reveals white crystalline deposits within the macular region of your patient. Which meds may cause such deposits?

A

Tamoxifen

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9
Q

What is Tamoxifen used for?

A

Tx of breast cancer

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10
Q

What are the potential ocular side effects of Tamoxifen?

A 
Corneal deposits
CME
Grey lesions in the RPE
Retinal hemorrhages
Optic disc edema
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11
Q

What posterior segment finding is common in long-term use of Plaquenil?

A

Bull’s eye maculopathy

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12
Q

What is Plaquenil typically used to treat?

A

Malaria
SLE
RA

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13
Q

What is Bull’s eye maculopathy?

A

Macular mottling and RPE disruptions

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14
Q

What is the primary ocluar side effect of Amiodarone?

A

Vortex keratopathy

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15
Q

What is vortex keratopathy?

A

Yellow/brown or white powdery corneal epithelial deposits located infero-centrally that spare the limbus

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16
Q

How do fluoroquinolones act?

A

Inhibit DNA gyrase

17
Q

If a fluoroquinolone is taken orally, what is a potential side effect?

A

Tendon rupture

18
Q

A 54-year old female has a very photophobic, red, OD. SLE reveals 3+ cells and flare in the AC. No evidence of inflammation OS. You diagnose irits and start Tx. You also notice that her IOP is 31. Which type of glaucoma med should NOT be prescribed? Which drug would be best?

A

Prostaglandin analogs

Best - Alphagan (brimonadine; alpha-agonist)

19
Q

You receive a sensitivity report on a sample that was sent to a local lab stating that the organism tested is “susceptible” to moxifloxacin. What does that mean?

A

The organism is sensitive to the normal dose of moxifloxacin

20
Q

If an antimicrobial report lists an organism as “intermediate”, what does that mean?

A

The organism is likely sensitive to a higher-than-normal dose of the tested drug

21
Q

What is a common side effect of oral administration of erythromycin

A

GI upset

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