Pharm

Question 1

Which oral medication has the most potential to cause a serious interaction with Amiodarone?

Answer 1

Warfarin

Question 2

What is Warfarin?

Answer 2

Anti-coagulant

Question 3

What is Amiodarone for?

Answer 3

Antiarrhythmic drug

Question 4

Why shouldn’t Amaiodarone and Warfarin be taken concurrently?

Answer 4

Enhances Warfarin’s MOA

-may result in increased clotting times and prolonged bleeding

Question 5

What demographic is most likely to be a steroid responder?

Answer 5

Children, especially those under 10

Question 6

What steroid base is used to minimize the chances of a steroid induced IOP increase?

Answer 6

Ester based

Question 7

What is Vicodin composed of?

Answer 7

Acetaminophen and hydrocodone

Question 8

Ad DFE reveals white crystalline deposits within the macular region of your patient. Which meds may cause such deposits?

Answer 8

Tamoxifen

Question 9

What is Tamoxifen used for?

Answer 9

Tx of breast cancer

Question 10

What are the potential ocular side effects of Tamoxifen?

Answer 10

Corneal deposits
CME
Grey lesions in the RPE
Retinal hemorrhages
Optic disc edema

Question 11

What posterior segment finding is common in long-term use of Plaquenil?

Answer 11

Bull’s eye maculopathy

Question 12

What is Plaquenil typically used to treat?

Answer 12

Malaria
SLE
RA

Question 13

What is Bull’s eye maculopathy?

Answer 13

Macular mottling and RPE disruptions

Question 14

What is the primary ocluar side effect of Amiodarone?

Answer 14

Vortex keratopathy

Question 15

What is vortex keratopathy?

Answer 15

Yellow/brown or white powdery corneal epithelial deposits located infero-centrally that spare the limbus

Question 16

How do fluoroquinolones act?

Answer 16

Inhibit DNA gyrase

Question 17

If a fluoroquinolone is taken orally, what is a potential side effect?

Answer 17

Tendon rupture

Question 18

A 54-year old female has a very photophobic, red, OD. SLE reveals 3+ cells and flare in the AC. No evidence of inflammation OS. You diagnose irits and start Tx. You also notice that her IOP is 31. Which type of glaucoma med should NOT be prescribed? Which drug would be best?

Answer 18

Prostaglandin analogs

Best - Alphagan (brimonadine; alpha-agonist)

Question 19

You receive a sensitivity report on a sample that was sent to a local lab stating that the organism tested is “susceptible” to moxifloxacin. What does that mean?

Answer 19

The organism is sensitive to the normal dose of moxifloxacin

Question 20

If an antimicrobial report lists an organism as “intermediate”, what does that mean?

Answer 20

The organism is likely sensitive to a higher-than-normal dose of the tested drug

Question 21

What is a common side effect of oral administration of erythromycin

Answer 21

GI upset