Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology Terms > Pharm 4 Drugs > Flashcards

Pharm 4 Drugs Flashcards

1
Q 
Epinephrine
MOA
Tx
Side Effects/Adverse Drug Rx
Contraindications
Toxicity
A

MOA: (adrenergic agonist) alpha = beta
TX: increases BP & blood flow, anaphylactic shock
SE: tachycardia, anxiety, tremor, elevated BP
C: none
Tox: Fatal arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
Norepinephrine
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic agonist) alpha > beta
TX: vasopressor
SE: elevated BP, tachycardia, anxiety, tremor
C: poor organ perfusion
Tox: perfusion problems (kidneys when in shock), cardiac arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q 
Isoproterenol
MOA
TX
SE/ADR
C
TOX
A 
MOA: (adrenergic agonist) pure beta
TX: certain types of shock to increase CO
SE: tachycardia, chest pain
C: tachycardias, angina
Tox: tachycardia, arrhythmia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q 
Amphetamine
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic agonist) same as epi, except effects last hours and is orally active
TX: ADD, ADHD, narcolepsy, severe depression refractive to antidepressants
SE: increased sys/dias BP, HR may decrease by reflex
C: ventricular tachyarrhythmia, HTN
Tox: tachycardia, arrhythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q 
Cocaine
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic agonist) local anesthetic with adrenergic agonist properties, potent CNS stimulant, blocks reuptake of catecholamines at adrenergic receptors
TX: vasoconstriction and anesthesia in upper respiratory passages
SE: cardiotoxicity, vasoconstriction
C: ventricular fibrillation, sensitivity to other local anesthetics
Tox: tachycardia, arrhythmia, MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q 
Phenylephrine
MOA
TX
SE/ADR
C
TOX
A 
MOA: (adrenergic agonist) pure alpha - vasoconstriction with no HR effects
TX: topical/systemic nasal decongestant
ADR: HTN
C: HTN, stroke
Tox: HTN
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q 
Pseudoephedrine
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic agonist) alpha > beta - vasoconstriction with modest effect on HR
TX: systemic decongestant (methamphetamine precursor)
ADR: tachycardia, HTN
C: HTN
Tox: tachycardia, arrhythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q 
Clonidine
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic antagonist), decreases adrenergic/sympathetic outflow, turns down the thermostat
TX: HTN, narcotic withdrawal, chronic pain
SE: sedation, dizziness, dry mouth/eyes, otherostatic hypotension w/o syncope, fatigue, sexual dysfunction
C: none
Tox: (none) potential for severe rebound HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q 
Doxazosin
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic antagonist), alpha 1 blocker
TX: HTN, BPH
SE: first dose syncope, drowsiness, dizziness, orthostatic hypotension
C: none
Tox: none (precaution - orthostatic hypotension)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
Propranolol
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic antagonist), non-selective (beta 1 &2) pure beta blocker
TX: lower BP and HR, angina (if no BP problem), HTN, rate control, tremor, social phobia
ADR: bradycardia, hypotension, heart block, fatigue, sexual dysfunction
C: heart block, reactive airway disease
Tox: heart block (avoid in patients with hx of anaphylaxis or severe asthma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
Atenolol
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic antagonist), selective beta 1, beta 1 > beta 2
TX: HTN, rate control
ADR: bradycardia, heart block, hypotension, fatigue, sexual dysfunction
C: heart block, reactive airway disease
Tox: heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q 
Albuterol
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic agonist), selective beta 2, beta 2 > beta 1
TX: bronchodilator in asthma/COPD/bronchitis
ADR: tachycardia, tremor, anxiety, elevated BP
C: none
Tox: cardiac arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
Labetolol
MOA
TX
SE/ADR
C
TOX
A 
MOA: (adrenergic antagonist), blocks alpha-1 & beta-1
TX: antihypertensive
SE: none
C: none
Tox: none
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q 
Monamine Oxidase Inhibitors (MAOIs)
MOA
TX
SE/ADR
C
TOX
A

MOA: (adrenergic agonist), interferes with reuptake/storage of adrenergic monoamine neurotransmitters like NE, Epi, dopamine
TX: antidepressant, keeps sympathetic agents in nerve synapse longer
SE: none
C: none
Tox: none

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q 
Acetylcholine
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic agonist), muscarinic and nicotinic - primary neurotransmitter of ANS
TX: none as rapidly metabolized (2-3 minute 1/2 life)
SE: SLUDGE
C: none
Tox: acetyl cholinesterase inhibitor poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q 
Bethanechol
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic agonist), muscarinic, contracts smooth muscle in bladder/bowel
TX: urinary retention, reverse anticholinergic agents of procedures (like when airways are treated to decrease secretions during procedures), treat ileus (paralyzed bowel)
SE: cholinergic
C: do not use to treat irreversible ach-esterase inhibition (such as in sarin gas/insecticide poisoning)
Tox: OD causes cardiac arrhythmias

17
Q 
Physostigmine
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic antagonist), acteylcholinesterase inhibitor (extends actions of ACh in body)
TX: glaucoma, cholinergic antagonist OD
SE: cholinergic
C: narrow angle glaucoma
Tox: usually minor as used as an ophthalmic soln

18
Q 
Pilocarpine
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic agonist), decreases intraocular pressure, reverses dilation of pupil & anticholinergtics in procedures
TX: glaucoma, eye drop soln to treat xerostomia (dry mouth)
SE: cholinergic
C: none
Tox: minor as used as an ophthalmic soln

19
Q 
Ipratropium
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic antagonist), direct muscarinic stimulant relieves bronchoconstriction, reduce secretions in chronic bronchitis
TX: respiratory inhalation for asthma/COPD/bronchitis as reduces secretions
SE: dry mouth, urinary retention, constipation, bradycardia
C: none (use only as inhalant)
Tox: cardiac arrhythmia in OD

20
Q 
Atropine
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic antagonist), muscarinic
TX: bradycardia, counteracts nerve gas, exposure to AChE inhibitors
SE: dry mouth, urinary retention, constipation
C: none when tx organophosphate insecticide poisoning
Tox: none

21
Q 
Scopolamine
MOA
TX
SE/ADR
C
TOX
A

MOA: (cholinergic antagonist), muscarinic
TX: prevents nausea/vomiting from motion sickness/post-anesthesia
SE: dry mouth, urinary retention, constipation, blurred vision
C: bradycardia (drops HR)
Tox: none

22
Q 
Oxybutynin
MOA
SE/ADR
C
TOX
A

MOA: (cholinergic antagonist), muscarinic
TX: overactive bladder/urge incontinence
SE: dry mouth, urinary retention, constipation, blurred vision
C: bradycardia
Tox: none

Pharmacology Terms (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions