Pharm Flashcards
Most potent to least derm formulation
-ointment
-cream (most easily absorbed)
-lotion
-solutions
how many steroid classes
7
most potent steroid class
1- never Rx in primary
least potent steroid topical class
7- otc creams
what potency is not prescribed in primary care
3-4
bactroban treats what gm+ bacteria
staph aureus and strep pyogenes
who to avoid bactroban in
pregnant people who are breastfeeding (not enough evidence)
how soon to see improvement with bactroban
3-5 days
antivirals can be harsh on what organ
kidneys- can lead to aki
antifungal safety alert
they are teratogenic and increase risk of spont. abortion and heart defects
what to look out for in those with antifungal meds
liver toxicity
Selenium sulfide is both a
antifungal and antiinfective
what is selenium sulfide used for
tinea versicolor
tinea capitus
how to dose for pinworms
1 dose then another 2 weeks later
terbinafine (lamisil) used for
tinea capitis
onchomycosis
duration of terbinafine tx for tinea capitis
2-4 weeks
duration of terbinafine for treatment of onchomycosis
6-12w
griseofluvin used for
tinea capitis
treatment duration of griseofulvin
6-8 weeks
pt teaching with griseofulvin
take with fatty food
what to monitor while on terbinafine
liver
what is permethrin used for
lice and scabies
how does permethrin work
overexcites the bug’s nervous system killin em
dosing info for permethrin for scabies
-apply to entire body neck down for 12 hours then wash off
-repeat in one week
dosing info for permethrin for lice
-apply to scalp and wash out right after
-only kills active lice and not eggs
-need 2nd treatment and nit combing
go-to initial acne treatment
benzoyl peroxide which dries and peels skin causing vacteria to shed off
what is sodium valproate (valporic acid)(depakote) used for
treats and prevents seizures
normal valporic acid level
50-100mcg
valporic acid tox level
> 100
SE of valporic acid
-wt gain
-hair loss with long term use
-hepato tox
what to monitor closely with valporic acid
liver
can we use depakote in pregnancy
NO
Phenytoin (dilantin) use
generalized and complex partial seizures
what must you tell pts with phenytoin (dilantin)
will decrease effectiveness of OCP
SE with dilantin (phenytoin)
-gingival hyperplasia
-hirsutism
what lab to monitor for with phenytoin (dilantin)
-avoid with liver issues (hepato tox)
-monitor LFT
What is tegretol (carbamazepine) used for
-trigeminal neuralgia
-seizures
how does tegretol (carbamazepine) work in trigeminal neuralgia
lessens pain signals sent to brain
Labs with tegretol (carbamazepine)
important se with tegretol (carbamazepine)
-mildly anticholinergic
Gabapentin use for
-peripheral neuropathy
-post herpatic neuralgia
SE of gabapentin
-dependent possible
-sedating
how does gabapentin work
works in brain by altering electrical activity and neurotransmitters
Topiramate uses
-seizure prevention
-migrane prevention
common se of topiramate
-wt loss
Avoid topiramate in
-hepatic or renal issues
-May increase risk of kidney stones
Which antidepressants can be used for migrain prophylaxis
-TCA (amatryptaline, nortryptaline)
What is nice about triptans
they are not all equivalant, if one doesnt work try another
do NOT use triptans with
-uncontrolled HTN
-MAOI
-CAD
How to take triptans
-take asap at migrane start
-only use 2x per week (risk for rebount HA if used more)
How does levodopa-carbidopa work
increased dopamine in brain
What symptom is levodopa-carbidopa best on
bradykanesia
consern with levodopa-carbidopa
hypotension = falls
Dopamine agonist examples
-ropinirol (requip)
-Pramipexole
How do dopamine agonists work
mimic dopamine in brain
Why are dopamine agonists used
to delay levodopa initiationas long as possible
DE of dopamine agonists
-impulse control issues
-edema
-hypotension- common
What is meclizine (bonine)
-antiemetic
-bppv
-labyrinthitis
med onset and duration of meclizine
onset of 30min
lasts 8-24 hours
why is meclizine good for old folks
-only mildly anticholinergic or sedating
how long to treat with iron
3-6mo