Crash Course Flashcards
What is the other name for canker sores
Apthous Stomatitis
What is the primary difference of location between apthous stomatitis and herpes
AS is typically inside the mouth while herpes is usually outside mouth/on lips
Ideal timeframe to begin treatment for oral herpes
48-72 hours
What is a chronic form of apthous stomatitis?
chronic ulcerative stomatitis (CUS)
What causes chronic ulcerative stomatitis
it is an autoimmune disorder but can be caused by lichen planis
What is the difference between CUS and apthous stomatitis
CUS lesions are larger in size and number and can take weeks to months to resolve
How to treat CUS
oral steroids and hydroxyfluroquin
What is keratosis pilaris commonly called
“chicken skin”
How to treat keratosis pilaris
emollients and moisturizers
(this condition is commonly outgrown)
What is the classic look of impetigo?
Honey crusted or yellow tinged lesions
What are the two most common bacterial causes of impetigo?
-Strep pyogenes
-Staph aureus
How to treat bollous impetigo
must have oral abx (keflex, dicloxacillin, doxy)
How to treat non-bollous impetigo
topical mupuricin ointment (bactroban)
What has a classic “christmas tree” pattern with a “herald patch”
Pityriasis rosea
Treatment for pityrasis rosea?
it usually self resolves
What does a brown recluse spider bite look like
-Deep purple spot with white halo around it
-VERY tender
How to treat rocky mountain spotted feaver
doxycycline
(even if pregnant or a kid)
When/where does the rash develop after a bite in rocky mt spotted fever
Starts 3-5 days after initial s/s and starts on palms and soles initially
What is erythema migrans
lyme disease
What does the rash of erythema migrans look like
“bulls eye” lesion
How to treat erythema migrans or lyme disease
1st- doxycycline
2nd- amoxicillin if pregnant or allergy to doxy
What is the other name for measles
Rubeola
What are the three distinguishing signs or symptoms of rubeola (measles)
“The three C’s”
-Cough
-congestion
-conjnctivitis
When does the rash develop in rubeola (measles)
3-5 days after the “3 C’s”
What are the oral lesions in rubeola (measles) and what do they look like
-Koplik spots
-Look like grains of sand with a red halo
-starts 3-5 days after the 3 c’s with the rash
How to prevent rubeola (measles)
vaccination at 12mo (live vax)
What is the most common symptom of mumps?
parotid gland swelling
“mumps with a jaw bumps”
Describe atinic keratosis
-dry, scaly lesion
-sun exposed area
-pink, yellow, tan, pale, brown in color
Treatment for atinic keratosis
– 5-FU (fluroicil)
– cryotherapy
What does actinic keratosis commonly lead to if untreated
squamous cell carcinoma
Describe squamous cell carcinoma
-red, scaly “crusty
-Bleeds easily
-sun exposed area
How to diagnosis squamous cell carcinoma
-biopsy
What do cafe au laid spots look like
-flat areas of darkened skin
if the patient has more than 6-8 cafe au lait spots, what other dx needs to be considered
-neurofibromatosis
What skin condition is usually described as “stuck on” brown spots
seborrheic keratosis which is benign
Describe basal cell carcinoma
-Telangiectasias (visible vessels)
-Shiny, waxy, pearly
Most common type of skin cancer
Basal Cell
(most common spice)
What to do if we suspect basal cell carcinoma
-Biopsy and refer to derm for removal
What is the other name for eczema
Atopic dermatitis
Describe atopic dermatitis
-flexor surfaces
-The itch that rashes
How to treat atopic dermatitis
-Emollients
-Topical steroids
What are the three a’s that commonly come together (atopic triad)
-atopic dermatitis
-asthma
-allergies
Describe plaque psoriasis
-Thick silvery scales
-Auspitz sign
-Koebner’s phenomenon
What is Auspitz sign
When plaque psoriasis lesions are scratched and pinpoint bleeding occurs
What is Koebner’s phenomenon
When trauma to the skin produces new lesions in plaque psoriasis pts
“Koby is always hurting himself”
How to treat plaque psoriasis
-topical steroids
-coal tar
-derm referral
When to start acyclovir for shingles
within 48-72 hours
How to treat contact dermititis
-topical steroids
-avoid irritant
Describe shingles
-follows across a dermatome
-vesicular
-proceeded by burning/tingling
Describe stage one pressure ulcer
Skin is intact but non-blanching
How to treat stage one pressure ulcer
Foam dressing- cushions the area
When is a pressure ulcer unstageable
when you cant see the wound bed
When is eschar on heels good?
-no s/s of infection
-seals out bacteria in DM pts
S/S of scabies
-Very itchy (everyone in house)
-Marks between fingers
How to treat scabies
Treat everyone with permethrin cream and wash everything in HOT water
(treat x2 often needed)
What is varcella
chicken pox
How is varcella often described
“lesions in various stages of healing”
When can kids with varcella return to school
when all lesions have crusted over
When is the varcella first given
at 12mo (live)
S/s of head lice
-itching of scalp day and night
Lice treatment
-Permethrin cream kills live ones
-Comb nits/eggs out
-wash everything in HOT water
Describe a molluscum contagiosum lesion
-flesh colored
-indent in the middle of lesion (umbillicated)
How to treat molluscum contagiosum lesions
-they self resolve
-consider sexual abuse if in the genital region on a kid
Describe antrax lesion
-ulcerated
-black
-painless
who might you see anthrax in
cattle farmers
how to treat anthrax
1st- ciprofloxacin
2nd- tetracyclines (doxy)
Risks of hidradenitis suppurativea
-obesity
-smoking
-genetics
Common areas for hidradenitis suppurativa
-groin
-thighs
-axilla
-breast folds
How to treat HS
Mild- warm comprsses
Severe- I&D, culture
Abx if infection is suspected
What is folliculitis
infection of the hair follicle plus surrounding skin
How to treat folliculitis
-Usually self resolves
-Warm compresses
-topical mupuricn ointment (bactroban)
-oral abx if severe (keflex, pcn)
Describe the rosacea rash
A facial rash that does NOT spare the nasal fold
(you dont spare your nose when smelling a rose)
How to treat rosacea
Metronidazole gel
Describe lupus rash
“mallar rash” or butterfly rash that does spare the nasal folds
What symptoms are consistent with sjogren’s syndrome
-dry eyes and mouth
what is erysipelas
a more superficial form of cellulitis
Describe erysipleas
-sharply defined/well demarcated borders
-superficial redness
How to treat erysipleas
-keflex
-PCNs
How to treat purulent cellulitis
(could be MRSA)
-Bactrim
-Clindamycin
-Doxycycline
How to treat non-purulent cellulitis
-Keflex
-PCNs
First line acne treatment
-Topical benzynol peroxide
Second line acne treatment
-topical abx (clindamycin)
-Topical retinoids (tretoinin)
Third line acne tx
oral abx (doxy)
4th line acne tx
-derm referral
What is the black box warning associated with isotretoinin
YOU CANNOT GET PREGNANT
What must you wear with tetracyclines?
SUNSCREEN
what can cause a geographical tongue
Spicy/hot foods
Can you scrape off oral candidiasis
yes
What disease causes “slapped cheeks”
Fifth’s disease
How do pts with fifth’s disease present
-Fever first
-Slapped cheeks rash
-lacy, net-like rash across body
When is a pt with fifths disease no longer contagious
when the rash APPEARS
Who needs to stay away from those with fifths disease?
pregnant people- fetal demise and miscarrage
what is enterobiasis
pin worms
s/s of enterobiasis
very itchy genital region at night
how to treat enterobiasis
mebendazole, abendazole
OTC pyrental pamoate
How to dx enterobiasis
scotch tape test
Abx for animal bites
augmentin
What is amblyopea
“lazy eye”
What is 20/200 vision
legal blindness
First step with any pt that comes in with a visual complaing
test acuity
what usually causes amblyopea
strabismus
what tests for color blindness
-anomaloscope
-ishihara chart
What cranial nerves are associated with the eye
II
III
IV
VI
CN II
optic- visual acuity
CNIII
oculomotor- focus
CNIV
trochler- downward and inward mvts
CN VI
abducens- outward mvt and side to side mvt
Which are lighter on fundoscopic exam arteries or veins
retinal arteries are thinner and lighter than veins
Describe a normal optic disc
-Sharp margins
What is papillidema
swelling of the optic disc- refer!
What fundoscopic exam findings are associated with HTN
-Papilledema
-AV nicking
-copper wire arteries
-flame hemmorrhages
What fundoscopic exam findings are associated with DM
-cotton wool spots
-blot hemorrhages
-microanurysms
-neurovascularazation
What are copper wire arteries on fundoscope
when the arteries look red
what is AV nicking on fundoscope
when an artery crosses a vein causing it to bulge at the intersection
what is neovascularization on fundoscope
formation of new tiny blood vessels
Describe the S/S of acute angle-closure glaucoma
-sudden SEVERE pain
-blurred vision
-eye feels firm (tonometry with increased IOP)
What is someone with acute angle glaucoma at risk of
blindness- refer to ED
Describe typical description of a retinal detachment
-“curtain being pulled over eye”
-Painless
-Frequent flashes/floaters/blurred vision
What are pts with retinal detachment at risk of
blindness- refer to ED
What is arcus senilis
grey halo around iris
What is xanthelasma
-yellow patches near corner of eye
When is xanthelasma considered benign
in old folks
how does cholesterol concerns present in the eye
-arcus senilis
-xanthelasma
What is the med term for pink eye
edenoviral conjuctivitis
Where is a pterygium
-encroaches on the corneaa
Where is a pinguecula
does NOT extend into the cornea
What is a chalazion and how to treat
-A blocked duct
TX: Warm compress
what causes a horeolum and how to treat
-Caused frequently by staph
-TX: warm compresses and abx
Which type of conjunctivitis starts bilaterally
allergic
Which type of conjunctivitis will have cervical lymphadenopathy
allergic
which type of conjunctivitis has serous and stringy drainage
allergic
Which type of conjunctivitis has purulent drainage
bacterial
Which conjunctivitis has preauricular and submandibular lymphadenopathy
viral
which type of conjunctivitis has no w`1
bacterial
what is leukoria
white reflex
when might you see leukoria
with cataracts
what is presbyopia and when does it usually begin
age related vision loss starting after 40
They will often state “my arms are too short”
What eye concern is often associated with bells palsey
corneal abrasions because they cannot close their eye- LUBE!
how to dx a corneal abrasion
-florascene stain
-tonometry if we need to R/O AAG
How would a pt with iritis present
-eye pain that is light sensitive
-poor visual acuity
-inflammation and swelling of the iris
how to treat iritis
refer! risk for blindness
How would a patient present with a cranial tumor
-dull persistent headache that is always in the same spot
-N/V
-Vision changes
-Behavioral/personality changes
How to DX cranial tumor
head CT
When will symptoms of a TIA vs Stroke dissapear
within one hour
What causes wernicke-korsakoff syndrome
-alcoholism related B1 vitamin deficiency (thiamine)
Which type is wernickes
receptive
which type is broca’s
expressive
Evaluation of stroke pts
“BE FAST”
-balance
-eyes
-face
-arm
-speech
-time
Describe a cluster headache presentation
-one sided
-tearing/runny nose
-occurs around same time daily
Cluster HA tx
-100% 02
-CCBs (verapimil)
-Imatrex?
How to definitively dx temporal arteritis
bx
What can temporal arteritis lead to
blindness
What is temporal arteritis also called
giant cell arteritis
Describe temporal arteritis s/s
-One sided HA
-possible visual impairment
-temple pain/pulsing
-increased ESR on bloodwork
Tx or giant cell arteritis
long term oral steroids
What condition is commonly associated with giant cell?
polymyalgia rheumatica
Describe a HTN HA
-occipital HA
-typically present upon awakening
How to tx HTN HA
-change or add meds
Describe migraine s/s
-difficulty with noise and light
-trobbing/pulsating
-N/V
-aura prior
What are the migrane abortive meds and who are they contraindicated in
-triptans
-Contraindicated in pts with uncontrolled HTN and those taking SSRIs
Which neurotransmitter is the issue with parkinsons
dopamine
What are the three main symptoms in parkinsons
-bradykanesia (most debilitating)
-tremors
-ridigity
What is the main tx of parkinsons
levodopa/carbadopa
Which two tests are helpful to dx meningitis
-brudzinski’s
-Kernig’s
Positive brudzinski’s
“B=Back of head”
Flexing back of head causes knees and legs to also flex
positive kernig’s
“K=Knee”
-Cant extend knee past 90 degrees without severe pain
What are the three “A”s associated with alxheimers
–Apraxia- inability to carry out skilled movements
–Aphasia
–Agnosia- inability to name objects/people
What is the overall goal of alzheimers tx
-slow progression
What tool is most often used to assess alzheimers
MMSE
CN order mnemonics
oh oh oh to touch and feel a great vein, ah heaven
CN function mnemonic
some say marry money but my brother says big brains matter more
Which nerve is associated with trigeminal neuralgia
the trigeminal- CN V
S/S of trigeminal neuralgia
-severe stabbing pain in the face (so severe that these folks are at risk of suicide)
First line treatment for trigeminal neuralgia
-tegretol (carbamazepine)
-Is an anticonvulsant
which CN is associated with bells palsey
CN VII
which two test assess CN VIII
Rinne and weber
Normal Rinne finding
air is 2x longer than bone conduction
Abnormal rinne finding
Bone conduction is longer than air
Normal weber finding
no lateralization to either ear
abnormal Weber finding
lateralization to either ear
S/S of meinere’s disease
-vertigo
-tennitus
-ear pressure
-nystagmus
Biggest concern with minere’s disease
risk for permanent hearing loss
Why do most pts stop SSRI/SNRI
-sexual dysfunction
-wt gain
What supplement can be used to treat depression
St Johns wart
When is St Johns wart contraindicated
with any other serotonin meds!
S/S of serotonin syndrome
-shivering
-shaking
-seizures
-tachy
-aggitation
What to do in no change in PHQ after starting SSRI 4-6 weeks ago
increase dose or look for other cause
Advise if N/V on SSRI/NRI
GI symptoms usually self resolve in a few weeks
When to try to taper off SSRI/NRI
Stay on for at least 6mo when well controlled
How to approach suicidal ideation
-be straight forward
-Ask about plan and refer for 72 hour hold if they do
Which SSRI should be avoided in the elderly and why
-Fluoxetine (prozac) because it has a very long half-life
- Tticyclics- anticholinergic SEs
Why are TCAs not first line for depression
Lots of anticholinergic SEs
(doxepin, nortriptyline, amitriptyline)
Which two antidepressants are safest in the elderly
-Sertraline
-Escitalopram
Both have safe SE profiles
Which SSRI is most sedating
Paxil (paroxetine)
Which SSRI should be avoided in an anxious patient and why
Fluoxetine (prozac)- it can produce jitteriness
Biggest SEs of ziprexa and seroquel?
-Wt gain
-Increase hyperlipedemia
-Get a lipid, BG and wt prior to initiating
Describe the two phases of bipolar
Mania- no sleep, impulse issues, over excitement
Depression- lack of motivation
What is commonly used to treat bipolar
Lithium
what is the therapeutic range for lithium
0.5-1.2
What are some issues with lithium
-Very narrow therapeutic range
-Long term SEs
-Induces hypothyroidism with long term use
S/S of PTSD
-nightmares
-hypervigilance
-exaggerated startle
-flash backs
insomnia
first line tx for PTSD
SSRIs but poorly researched
Tx for seasonal affective disorder
more light
Which enzyme pathway is responsible for why we cant give SSRI with st. johns wart
CYP3A4
Which pathway impacts an asian’s ability to metabolize pain meds and reduce their effectiveness
CYP2C19
What is the ASCVD risk cutoff for initiating a statin
7.5%
Normal total cholesterol
<200
Normal HDL
40-60
Normal LDL
<100
Normal triglycerides
<150
How often to check lipids if no risk factors present
Q5y
How often to recheck lipid after initiating statin
Q1-3m then yearly
Which two HMG CoA reductase inhibitors can be high intensity
atorvastatin and rosuvastatin
S/S to watch for with statins
-new muscle pain (check CK, stop statin, can lead to acute renal failure)
-S/S of jaundice (draw LFT)
What dietary thing to avoid with statins
grapefruit juice
When should you be concerned with triglycerides
when it is over 500
When triglycerides are over 500, what to tx and why
fenofibrate to prevent pancreatitis
JNC8 HTN goal
<140/90
When to initiate treatment in those older than 60? for the JNC8
> 150/90
Goal for AHA/ACC
<130/80
Stage 1 HTN treatment with ASCVD cutoff for AHA at
10%
ACE monitoring
-Renal function: GFR, BUN, Creat
-K+ (at risk for hyperkalemia)
-Watch for angioedema and cough
When do we switch to an ARB
when they fail an ACE (me)
TZD is bad for who?
-DM (increase BG)
-Gout (increases uric acid)
-Hyperlipidemia (increases triglycerides)
Which pt is a thiazide particularly good for?
those with osteoporosis because it stimulates osteoblasts and Ca+ retention
Typical SE of CCB
-ankle edema
-HAs
-Worsens GERD symptoms (relaxes sphincter)
Renal protective antiHTN
ACEi
What BP meds are safe in pregnancy
“New Little Momma”
-Nifedipine
-Labetaolol
-Methyldopa
(do not give ACE, ARB, Statins, Methotrexate)
What are the two most common causes of CKD
HTN and DM
What is ideal for isolated systolic hypertension in the elderly
(caused by stiffening of blood vessels)
CCB because it relaxes the smooth muscle
(Apparently Tzds as well)
What is it called when there is a variance in inspiration and expiration?
respiratory sinus arrhythmia
In what population is respiratory sinus arrhythmia common in
-Associated with young and healthy people
-Doesnt need treatment
What is pulsus paradoxus
When there is a 10+pt drop in systolic BP upon inspiration
-EMERGENCY as it can indicate a cardiac tampanaude or status asthmaticus
Why are CCBs not recommended in HF?
decreases the force of contraction
(they should also DC NSAIDS as it increases Na+ retention)
Diagnostic HF labs/tests
-BNP
-EKG
-CXR- cardiomegaly
-Echo- measures EJ
what is the ejection fraction in those with HF
<40 is HF
What kind of sound will you hear with HF
S3 (associated due to fluid overload)
(also heard in pregnancy)
Why are TZDs and CCBs not used in HF?
both cause edema
When should a HF pt call you with increased weight
if they gain more than 2kg per day
(increase/add a diuretic)
Why avoid NSAID with HF?
Encourages Na+ retention
A fib is the 1# risk for what
clot, stroke
Describe ekg of a-fib
irregularly irregular with NO P wave
What two meds will a chronic A-fibber be on
-Anticoags- stroke prevention
-BBlocker for rate control
Normal INR for those not on antigcoag
around 1
Therapeutic INR on warfarin
2-3
Antidote for warfarin
Vitamin K
When to give Vitamin K
-Active bleeding
-INR over 10
How to treat raynaud’s?
-CCB (relaxes small vessels)
-Avoid triggers (cold, stress)
Order of valve
Aortic
pulmonic
tricuspid
mitral
What makes the S1 sound
-Closure of the mitral and tricuspid valves (AV)
What makes an S2 sound
Closure of the semi-lunar valves: aortic and pulmonic
Which is the only sound heard at the base of the heart
S2
When is the S3 heard
in cases of fluid overload like HF and Pregnancy
When is an S4 heard
In uncontrolled HTN with left ventricular hypertrophy