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IMSE 311 > Phagocytosis > Flashcards

Phagocytosis Flashcards

1
Q

Process by which specialized cells engulf and destroy foreign particles such as microorganisms or damaged cells.

A

Phagocytosis

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2
Q

Most important phagocytic cells

A

Macrophages and Neutrophils

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3
Q

A cell that ingests microorganisms and foreign particles.

A

Phagocytic cells

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4
Q

Extremely small, relatively simple prokaryotic microorganisms traditionally classified with the fungi as Schizomycetes.

A

Bacteria

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5
Q

Something that suggests the presence or existence of a fact, condition, or quality

A

Signs

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6
Q

Any indication of a disease or injury perceived by the patient

A

Symptoms

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7
Q

The site of the experiment should be..

A

Sterilized

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8
Q

Blood should be drawn by an…

A

Aseptic technique

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9
Q

A minimum of 2 ml of blood is put into the

A

Green-top evacuated tube

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10
Q

A green top tube has what kind of anti-coagulant

A

Heparin

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11
Q

(True or False)
The microscope shouldn’t be placed on a plain, stable surface.

A

False

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12
Q

(True or False)
The voltage of the power supply should be inclined with that of the equipment.

A

True

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13
Q

What organism should we use in this experiment

A

Bacillus subtilis or Staphylococcus epidermidis

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14
Q

What stain is used in the experiment

A

Wright stain

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15
Q

How many drops of buffy coat should be added

A

4-8 drops

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16
Q

How many drops of bacterial broth culture is added?

A

2-3 drops

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17
Q

(True or False)
Place 2 drops of the incubated specimen on a glass slide and prepare a smear.

A

False

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18
Q

(Interpret)
Demonstration of the engulfment of bacteriaz

A

Positive

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19
Q

(Interpret)
No engulfment of bacteria

A

Negative

20
Q

(True or False)
The procedure may produce false-negative results if the blood specimen is not fresh.

A

True

21
Q

(True or False)
Coagulase-positive Staphylococcus specimen may produce false-positive results.

A

True

22
Q

(Interpret)
Bacteria is not intracellular

A

Negative

23
Q

(True or False)
The bacteria must be intracellular and not extracellular for the test to be positive.

A

True

24
Q

The failure of phagocytes to engulf bacteria can support the diagnosis of what?

A

Neutrophilic dysfunction

25
Q

Action of a specialized group of phagocytic cells that provide a defense mechanism against invasion by engulfing foreign particulate matter.

A

Phagocytosis

26
Q

Constitute the major cellular components (mast cells, neutrophils, macrophages)

A

Phagocytes

27
Q

Activated phagocytes have increased surface receptors that allow for adherence to the bacterium

A

Initiation

28
Q

Process in which cells tend to move in a certain direction under the stimulation of chemical substance.

A

Chemotaxis

29
Q

Shows positive chemotaxis

A

Leukocytes

30
Q

Away from the stimulating substances

A

Negative Chemotaxis

31
Q

Toward the stimulating substances

A

Positive Chemotaxis

32
Q

By active ameboid motion; final structure is known as vacuole/phagosome; bacteria must be hydrophobic than the phagocyte

A

Engulfment

33
Q

Interact with the surfaces of bacteria, rendering them acceptable to the phagocyte

A

Opsonin

34
Q

Engulfment of antigen

A

Phagosome

35
Q

Fusion of phagosome and lysosome

A

Phagolysosome

36
Q

Minute cell particles that contain certain hydrolytic enzymes and peroxides approach the phagosome, fuse with it, rupture, and discharge content to it.

A

Digestion

37
Q

Has defensins and cathepsin-G

A

Oxygen independent

38
Q

Formation of superoxide —> hydrogen peroxide —> hypochlorite

A

Oxygen dependent (oxidative burst)

39
Q

Physical contact between the phagocytic cell and the microorganism occurs, aided by opsonins.

A

Adherence

40
Q

Outflowing of cytoplasm to surround the microorganism

A

Engulfment

41
Q

Microorganism is completely surrounded by a part of the cell membrane.

A

Formation of phagosome

42
Q

Lysosomal granules contact and fuse with the phagosome.

A

Granule contact

43
Q

Contents of the lysosome are emptied into this membrane-bound space.

A

Formation of phagolysosome

44
Q

Uses hydrolytic enzymes

A

Digestion of microorganisms

45
Q

Contents of phagolysosome are expelled to the outside by exocytosis

A

Excretion

IMSE 311 (4 decks)

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