Phaeochromocytome

Question 1

what is a phaeochromocytoma?

Answer 1

rare catecholamine producing tumour (adrenaline, noradrenaline, dopamine)
(family history is crucial)

Question 2

Where do phaeochromocytomas arise from?

Answer 2

sympathetic ganglia cells which are collections of chromaffin cells
usually found within the adrenal medulla

Question 3

What is the classical triad (symptoms and signs) of phaeochromocytomas?

Answer 3

episodic headache, sweating and tachycardia (+/- BP change)
Symptoms may be precipitated by straining, exercise, stress, abdominal pressure, surgery, or by agents such as -blockers, IV contrast agents, or the tricyclics.