Phaeochromocytoma Flashcards

1
Q

what cells in adrenal glands secrete adrenaline

A

chromaffin cells

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2
Q

what is a phaeochromocytoma

A

adrenaline secreting tumour of the adrenal medulla

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3
Q

what is the 10% rule in pheochromocytoma

A

10% are bilateral
10% are familial
10% are malignant
10% are extra-adrenal

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4
Q

what genetic condition are phaeochromocytomas associated with

A

MEN 2

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5
Q

Symptoms of phaeochromocytoma

A
sweating 
hypertension 
headahce
palpiations
flushing 
anxiety
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6
Q

investigation

A

3x 24 hour urine collections for catecholamines/metanephrines
abdominal CT/MRI

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7
Q

Management

A

step 1: alpha blockers (phenoxybenzamine)
step 2: beta blockers (propranolol)
step 3: surgery (laprascopic adrenalectomy)

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