Phaeochromocytoma Flashcards
1
Q
what cells in adrenal glands secrete adrenaline
A
chromaffin cells
2
Q
what is a phaeochromocytoma
A
adrenaline secreting tumour of the adrenal medulla
3
Q
what is the 10% rule in pheochromocytoma
A
10% are bilateral
10% are familial
10% are malignant
10% are extra-adrenal
4
Q
what genetic condition are phaeochromocytomas associated with
A
MEN 2
5
Q
Symptoms of phaeochromocytoma
A
sweating hypertension headahce palpiations flushing anxiety
6
Q
investigation
A
3x 24 hour urine collections for catecholamines/metanephrines
abdominal CT/MRI
7
Q
Management
A
step 1: alpha blockers (phenoxybenzamine)
step 2: beta blockers (propranolol)
step 3: surgery (laprascopic adrenalectomy)