Random Flashcards

1
Q

what conditions is growth hormone given for

A

Turners syndrome
Prader-Willi
Proven growth hormone deficiency

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2
Q

what can decrease the absorption of levothyroxine

A

Iron supplements

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3
Q

what cardiac problems can hyperthyroidism cause

A

high output cardiac failure

AF

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4
Q

genetic profile Kleinfelters

A

47 XXY

- High LH, low testosterone

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5
Q

symptoms of Kleinfelters

A
tall
lack of secondary sexual characterises
small, firm testis 
infertile
gynaecomastia
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6
Q

drug given in cerebral metastasis

A

dexamethasone to decrease cerebral oedema

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7
Q

what causes impaired hypoglycaemic awareness in patients with diabetes

A

neuropathy of autonomic nervous system

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8
Q

blood glucose targets T1DM

  • on waking
  • before meals
A

5-7 mmol on waking

4-7 mmol before meals

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9
Q

what is Nelsons syndrome

A

a pituitary adenoma releasing ACTH after bilateral adrenalectomy

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10
Q

HbA1c range for pre-diabetes

A

42-47 mmol

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11
Q

what is secondary hypothyroidism due to? what do thyroid function tests show?

A

pituitary insufficiency

low TSH low T4

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12
Q

What drugs can cause galactorrhea

A

metoclopramide
domperidone
chlorpromazine

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13
Q

what is a neuroblastoma

A

tumour of neural crest of adrenal medulla

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14
Q

when does a neuroblastoma present?

how does it present?

A

median age 20 months old

  • abdo mass
  • weight loss
  • pallor
  • bone pain
  • hepatomegaly
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15
Q

what is raised in a neuroblastoma

A

VMA + HVA levels

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16
Q

1st line treatment of a prolactinoma

A

bromocriptine

17
Q

what diabetic drug increases risk of fractures

A

pioglitazone

18
Q

mechanism of action orlistat

A

inhibits gastric + pancreatic lipase

- aids weight loss

19
Q

features of MEN 1

A

parathyroid adenoma
pituitary adenoma
pancreatic tumour

20
Q

features of MEN 2

A

phaeochromocytoma
medullary thyroid cancer
parathyroid adenoma

21
Q

what happens to dose of hydrocortisone + fludrocortisone if patient with Addisons becomes unwell

A

double hydrocortisone dose

fludrocortisone dose remains the same

22
Q

pepper pot skull indicates what pathology?

A

primary hyperparathyroidism

23
Q

tender goitre indicates what?

A

subacute thyroiditis

24
Q

what is Waterhouse friderichsen syndrome

A

adrenal gland failure due to bleeding into the adrenal gland

- typically caused by meningitis

25
Q

treatment of toxic multi nodular goitre

A

radioactive iodine

26
Q

how many units of insulin are in 1ml

A

100

27
Q

what is Kallmans syndrome

A

genetic GnRH deficiency

- associated with anosmia