Random Flashcards
what conditions is growth hormone given for
Turners syndrome
Prader-Willi
Proven growth hormone deficiency
what can decrease the absorption of levothyroxine
Iron supplements
what cardiac problems can hyperthyroidism cause
high output cardiac failure
AF
genetic profile Kleinfelters
47 XXY
- High LH, low testosterone
symptoms of Kleinfelters
tall lack of secondary sexual characterises small, firm testis infertile gynaecomastia
drug given in cerebral metastasis
dexamethasone to decrease cerebral oedema
what causes impaired hypoglycaemic awareness in patients with diabetes
neuropathy of autonomic nervous system
blood glucose targets T1DM
- on waking
- before meals
5-7 mmol on waking
4-7 mmol before meals
what is Nelsons syndrome
a pituitary adenoma releasing ACTH after bilateral adrenalectomy
HbA1c range for pre-diabetes
42-47 mmol
what is secondary hypothyroidism due to? what do thyroid function tests show?
pituitary insufficiency
low TSH low T4
What drugs can cause galactorrhea
metoclopramide
domperidone
chlorpromazine
what is a neuroblastoma
tumour of neural crest of adrenal medulla
when does a neuroblastoma present?
how does it present?
median age 20 months old
- abdo mass
- weight loss
- pallor
- bone pain
- hepatomegaly
what is raised in a neuroblastoma
VMA + HVA levels
1st line treatment of a prolactinoma
bromocriptine
what diabetic drug increases risk of fractures
pioglitazone
mechanism of action orlistat
inhibits gastric + pancreatic lipase
- aids weight loss
features of MEN 1
parathyroid adenoma
pituitary adenoma
pancreatic tumour
features of MEN 2
phaeochromocytoma
medullary thyroid cancer
parathyroid adenoma
what happens to dose of hydrocortisone + fludrocortisone if patient with Addisons becomes unwell
double hydrocortisone dose
fludrocortisone dose remains the same
pepper pot skull indicates what pathology?
primary hyperparathyroidism
tender goitre indicates what?
subacute thyroiditis
what is Waterhouse friderichsen syndrome
adrenal gland failure due to bleeding into the adrenal gland
- typically caused by meningitis
treatment of toxic multi nodular goitre
radioactive iodine
how many units of insulin are in 1ml
100
what is Kallmans syndrome
genetic GnRH deficiency
- associated with anosmia
