Perseris Flashcards
Generic
Risperidone
Manufacturer
Indivior
Dosage
90mg and 120mg
How supplied
One pouch with risperidone powder
One pouch with delivery system syringe and desiccant
One 18 gauge 5/8th needle
Stay state
After first dose (1 month)
Indication
Treatment of schizophrenia in adults
Study
1 8 week trial, every 4 weeks vs. placebo. PANSS total score
Loading dose
N/A
Maintenance
Maintenance 90 or 120 dose mg
How often
Once monthly
Administration
Sub-Q in abdomen or back of upper arm
Adverse events
Increased weight, sedation/somnolence, muscoskeletal pain
Special population
Pregnancy: EPS and withdrawals symptoms in neonates with third trimester exposure
Renal and hepatic impatient: titrate on oral up to our less than 3mg before initiating at 90mg
Drug interactions
Carbamazepine and other 3YP3A4 inducers decrease plasma concentrations of riperidone
Fluoxetine, paroxetine, and other strong CYP2D6 inhibitors increase risperidone concentrations
Storage
Refrigerate 36-46F. Allow come to room temperature. 68F-77F more than 15 minutes before mixing
Can be stored unopened at room temperature for 30 days. After removal from refrigeration, use within 30 days