Invega Sustenna

Question 1

Generic name

Answer 1

Paliperidone palmitate

Question 2

Dosage form/strength

Answer 2

39mg/0.25 mL
78mg/0.5 mL
117mg/0.75mL
156mg/1mL
234mg/1.5mL

Question 3

How is it supplied?

Answer 3

Pre-filled with two needles
1 1/2 inch 22 gauge
1 inch 23 gauge

Question 4

Steady state

Answer 4

8-9 months

Question 5

Indications

Answer 5

Schizophrenia
Schizoaffective
Adjunct to mood stabilizer and antidepressants

Question 6

Before initiating criteria

Answer 6

Establish tolerability with oral paliperidone or risperidone

Question 7

Loading dose

Answer 7

Recommended initiation with dose of 234mg on day 1 and then 156mg one week later

Question 8

How often

Answer 8

Once a month

Question 9

Administration site

Answer 9

Deltoid or gluteal muscle

Question 10

Adverse reactions

Answer 10

Injection site reactions,
somnolence/sedation,
Dizziness,
Akathisia,
EPS

Question 11

Specific population use

Answer 11

May cause EPS and withdrawal symptoms in neonates with third trimester exposure

Question 12

Drug interactions

Answer 12

Strong CYP3A4 inducers
P-gp during a dosing interval

Question 13

Storage

Answer 13

Room temperature 59 F - 86 F
Do not mix