Abilify Maintena

Question 1

Generic name

Answer 1

Aripiprazole

Question 2

Manufactured

Answer 2

Otsuka

Question 3

Dosing

Answer 3

300mg
400mg
Lyophilized powder for reconstitution in single dose, pre filled dual chamber or single dose vial

Question 4

Supplied

Answer 4

Prefilled syringe kit
Three needeles
23G, 1 inch/25mm
22G, 1.5 inch/38mm
21H, 2 inch/51mm
Depending on administration sire and patient obesity
Single use kits also has 1 5mL sterile water

Question 5

Steady state

Answer 5

By 4th dose (4 months)

Question 6

Indication

Answer 6

Schizophrenia
Maintenance monotherapy BP1

Question 7

Criteria prior

Answer 7

Establish tolerability with oral first

Question 8

Loading dose

Answer 8

14 days of oral (10 to 20mg) aripiprazole or current oral antipsychotics prior to initiating Maintena

Question 9

Maintenance dosing range

Answer 9

400
Monthly

Question 10

Administration site

Answer 10

Deltoid or gluteal muscle

Question 11

Food requirement

Answer 11

No

Question 12

Adverse events

Answer 12

Increased weight gain
Akathisia
Injection site
Sedation

Question 13

Specific population

Answer 13

EPS and withdrawal symptoms in neonates with third trimester exposure

Question 14

Drug interaction

Answer 14

CYP2D6 inhibitors
CYP3A4 inhibitors
CYP3A4 inducers

Question 15

Storage

Answer 15

Prefilled dual chambers, store below 86F, do not freeze
Protect from light
Vial store at 59-86F