Peroxisomes Flashcards
-im both animals and plants
-works closely with lysosomes
-for degradation/breakdown
peroxisomes
peroxisomes in liver and kidney (for ____ ).
detoxification
functions of peroxisomes
-breakdown by oxidation of fatty acids to sugar
-breakdown of H202, catalyzed by enzyme catalase
-breakdown of excess purines to uric acid
-synthesis of cholesterol
-synthesis of bile acids
-synthesis of lipids used to make myelin
-peroxisomes are not made
-deficiency/defect in enzymes
peroxisomal biogenesis disorder
-defect in importing proteins into peroxisomes, giving rise to “ghost peroxisomes”
-leads to empty peroxisomes
zellweger syndrome
-autosomal recessive disorder on chromosome 10
-accumulation of phytanic acid in the brain, tissues, and blood.
-defective peroxisomal enzyme
-short 4th toe
refsum’s disease
-deficiency in B-oxidation of long chain fatty acids
ALD (Adrenoleukodystrophy)
-little “transfer ships”
-storage of ions, pigments, proteins, and defensive compounds
vacuoles and vesicles
phagocytosis and fuse with lysosomes
food vacuoles
in freshwater protists, pump excess H2O out of cell
contractile vacuole
found in many mature plant cells
central vacuoles