Peritonitis Flashcards

1
Q

Define peritonitis?

A

inflammation of the peritoneal lining of the abdominal cavity

it can be localised to one part of the peritoneum or generalised

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2
Q

what are the causes of localised peritonitis?

A

appendicits

cholecystitis

diverticulitis

salpingitis ( inflammation of fallopian tubes)
duodenal ulcer

intestinal obstruction

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3
Q

outline the aetiology and risk factors of primary generalised peritonitis?

A

Bacterial infection of the peritoneal cavity without an obvious source

  • Could be via haematogenous or lymphatic spread or ascending infection from the female genital tract)

Risk Factors

  • Ascites
  • Nephrotic syndrome
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4
Q

outline the aetiology of secondary peritonitis?

A

Caused by bacterial translocation from a localised focus

Could be non-bacterial due to spillage of bowel contents, bile and blood (e.g. perforated peptic ulcer)

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5
Q

outline the epidemiology of primary peritonitis?

A

rare- more commonly seen in adolescent females

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6
Q

outline the epidemiology of localised and secondary generalised peritonitis?

A

COMMON in surgical patients (perforated ulcer or appendicitis)

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7
Q

what is tertiary peritonitis?

A

persistent or recurrence of intraabdominal infection after adequate therapy of primary or secondary peritonitis

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8
Q

what are the presenting symptoms of peritonitis?

A

Do a full SOCRATES for peritonitis

Inflammation of the parietal peritoneum is usually continuous, sharp, localised, sudden exacerbated by movement and coughing/ breathing

Symptoms may be vague in those with liver disease and ascites (due to confusion caused by encephalopathy)

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9
Q

what other signs should you be aware of for peritonitis?

A

Check vital signs and look for signs of dehydration or compromised perfusion (e.g. due to sepsis or hypovolaemia)

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10
Q

what are the signs of localised peritonitis?

A

Tendernesson examination

Guarding– spasm of muscle on palpation

Rebound tenderness

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11
Q

what are the signs of generalised peritonitis?

A

Very unwell

Systemic signs of toxaemia or sepsis (e.g. fever, tachycardia)

The patient will lie still

Shallow breathing

Rigid abdomen

Generalised abdominal tenderness

Reduced bowel sounds- as it hurts when bowels move (may be absent due to paralytic ileus)

  • Ileus is the medical term for the lack of movement somewhere in the intestines leading to a buildup and potential blockage of food material. Paralytic ileus is obstruction of the intestine due to paralysis of the intestinal muscles

DRE may show anterior tenderness (suggests pelvic peritonitis)

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12
Q

What bloods are needed to investigate peritonitis?

A

FBC

U&Es

LFTs

Amylase – acute pancreatitis causes similar signs so check amylase!!

CRP

Clotting

Group & Save or Cross-match

Blood cultures– polymorphonuclear leukocytosis (more neutrophils, basophils and eosinophils)

Pregnancy test

ABG

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13
Q

what imaging is needed to investigate peritonitis?

A

Erect CXR (check for air under the diaphragm)

  • Sitting up for 10 mins

AXR (check for bowel obstruction)

USS or CT abdomen

Laparoscopy

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14
Q

what investigations would you do if there is ascites?

A

Ascitic tap and cell count

Spontaneous Bacterial Peritonitis (SBP) = > 250 neutrophils/mm3

Gram stain and culture

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15
Q

outline the management of localised peritonitis?

A

Depends on CAUSE

Some causes may require surgery (e.g. appendicitis)

Some causes can be treated with antibiotics (e.g. salpingitis)

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16
Q

outline the management of generalised peritonitis?

A

Patient may be at risk of DEATH from sepsis or shock

IV fluids

IV antibiotics

Urinary catheter

NG tube

Central venous line (to monitor fluid balance)

Laparotomy

  • Remove the infected or necrotic tissue
  • Treat cause
  • Peritoneal lavage

Primary Peritonitis - should be treated with antibiotics

17
Q

outline the management of spontaneous bacterial peritonitis ( SBP)

A

Quinolone antibiotics

OR

Cefuroxime + Metronidazole

18
Q

What are the early and late complications of peritonitis?

A

Early

  • Septic shock
  • Respiratory failure
  • Multiorgan failure
  • Paralytic ileus
  • Wound infection
  • Abscesses

Late

  • Incisional hernia
  • Adhesions
19
Q

summarise the prognosis of patients with peritonitis?

A

Localised peritonitis usually resolves with treatment of the underlying cause

Generalised peritonitis has a much higher mortality (30-50%)

Primary peritonitis has a good prognosis with antibiotic treatment

SBP has a mortality > 30% if diagnosis and treatment is delayed