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CVS 2023 > Peripheral venous and arterial disease > Flashcards

Peripheral venous and arterial disease Flashcards

1
Q

Lower limb venous system divided into

A

Superficial and Deep veins

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2
Q

Where are deep veins and superficial veins located?

A

Superficial: Within subcutaneous tissue
Deep: Underneath deep fascia with major arteries

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3
Q

Movement of blood veins

A

Superficial to deep veins

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4
Q

Deep veins lower limb (9)

A

Common iliac –> external iliac –> common femoral (branches into deep and superficial femoral) –> popliteal –> anterior/posterior tibial and peroneal

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5
Q

Superficial veins lower limb

A

Femoral vein –> long saphenous vein (anteromedial) (always in front of medial malleolus)

Popliteal vein –> short saphenous vein (posterolateral)

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6
Q

Bridges between deep and sueprficial veins

A 
Femoral vein (gives rise to long saphenous)
Popliteal vein (gives rise to short saphenous)
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7
Q

Name the calf muscle pump muscles and describe what they do

A

Gastrocnemius and Soleus

Soleus and gastrocnemius muscles in the leg push the blood against gravity back towards heart

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8
Q

What is the calf muscle pump also known as?

A

AKA ‘the peripheral heart’

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9
Q

How is calf muscle pump assisted?

A
  • Valves open = blood pushed into deep veins = valves close to prevent retrograde movement of blood (back flow of blood = perforating valves open again and blood fills the deep vein from the superficial vein, through the perforating vein
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10
Q

What occurs during exercise to venous pressure in the foot?

A

Venous pressure in the foot is reduced

When standing still, pressure increases

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11
Q

What is the most common cause of peripheral vascular disease?

A

Atheroma

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12
Q

What do you see in the early part of peripheral venous disease?

A

Varicose veins

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13
Q

What are varicose veins?

A

Veins that have become twisted and tortuous due to the valves being ineffective

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14
Q

What is a common site for varicose veins?

A
  • Saphenous veins
  • They are superficial so you can see them on the surface
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15
Q

Describe how varicose veins occur

A
  • Starts with WALL OF VEINS WEAKEN
  • Then varicosities develop
  • And valve cusps separate causing valves to become incompetent
  • The flow through the veins becomes slowed = stasis and pooling or even reversed
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16
Q

How do varicose veins affect blood flow?

A

Valves ineffective, slow or even reversed blood movement (blood pooling and stasis)

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17
Q

Do varicose veins usually cause problems?

A
  • Don’t normally cause problems in own right but they can present symptomatically
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18
Q

Shape of varicose veins

A

Tortuous and twisted

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19
Q

Symptomatic presentation peripheral venous disease (9)

A
  • Heaviness
  • Aching
  • Muscle cramps
  • Throbbing
  • Leg cramps
  • Pain
  • Ankle swelling
  • Varicose eczema
  • Haemorrhage- bleeding from damaged veins

Along the affected vein

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20
Q

Risk factors peripheral venous disease (5)

A 
Age
Family history
FEMALE
Number of births
If your occupation involves long periods of standing
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21
Q

Complications of peripheral venous disease

A
  • Superficial vein thrombophlebitis (inflammation from clot in vein) - painful erythematous follows varicose veins
  • Increased risk of DEEP vein thrombosis
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22
Q

What is chronic venous insufficiency? (3)

A
  • More advanced disease
  • Reflux and/or obstruction causing venous hypertension
  • (50% people develop it within 10 years of a DVT)
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23
Q

Complications chronic venous insufficiency (4)

A

Lipodermatosclerosis (inflammation and thickening of subcutaneous fat)
Haemosiderin staining (brawny oedema)
Venous ulceration
Venous Eczema

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24
Q

Why does do you get haemosiderin staining in chronic venous insufficiency? (4)

A
  • Increase in hydrostatic pressure in post-capillary venules
  • Leaking of RBC
  • Haem oxidsed by macrophages (haemosiderin forms)
  • Rusty looking leg
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25
Q

Describe venous eczema (6)

A
  • Chronic
  • Itchy
  • Red
  • Swollen
  • Tight
  • Can lead to Lipodermatosclerosis
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26
Q

What can venous eczema lead to? (2)

A
  • Lipodermatosclerosis (inflammation and thickening of subcutaneous fat)
  • Hard to the touch compared to other fatty tissues above or below
27
Q

Where do ulcers usually form?

A

Around hard nodular areas (eg medial malleolus)

28
Q

Describe venous ulceration (6)

A
  • Chronic
  • Painful
  • Often develop around hard nodular areas like medial malleolus
  • Result of venous hypertension
  • Very distressing and challenging to treat
  • Treat ulcer and the cause
29
Q

Why does calf muscle pump fail?

A

Because calf muscles aren’t being used properly to cause plantar flexion at the ankle joint during walking

Immobile people at risk

30
Q

Which people are at risk of calf muscle pump failure? (4)

A
  • Injured/immobile patients
  • Elderly (May shuffle or be immobile)
  • Parkinsons patients who end up shuffling instead of walking properly (No plantar flexion)
31
Q

What occurs during calf muscle pump failure? (4)

A 
- Deep vein incompetence - retrograde flow - system overwhelmed
- Superficial vein incompetence - blood moves from deep to superficial veins instead of superficial to deep 
- Calf muscle pump overflows
 - Leads to venous hypertension
32
Q

Treatment venous hypertension/calf muscle pump failure?

A

Ligation (tie off) and vein stripping (tying/removing)

  • This improves ulceration
33
Q

Arterial thrombus vs venous thrombus

A

Different pathophysiology

Arterial:

  • Most common cause is atheroma
  • Platelet rich, they are activated and aggregate to form a plaque

Venous:

  • stasis + another factor( ie anything = that causes hypercoagulative state?) (pregnancy, the pill, trauma, dehydration, chemo - )
  • low flow and little plates component FIBRIN RICH
34
Q

Virchows traid

A

Hypercoagulable state
Vessel wall damage
Flow problem (stasis)

35
Q

What is deep vein thrombosis?

A

Clotting of blood in a deep vein which impaires venous return

36
Q

Deep vein thrombosis common site

A

Calf

37
Q

Describe the inflammatory response produced following thrombosis (3)

A
  • Pain
  • Swelling (asymmetrical)
  • Redness
38
Q

Signs DVT (7)

A 
Variable in severity and frequency:

- Calf tenderness
- Warmth
- Redness
- Distended and visible superficial veins
- Swollen leg (oedema)
- Pyrexia with no other obvious
- Asymmetry
39
Q

How to test suspected DVT

A

Wells score (assess risk) - pre-test probability can help form part of diagnosis

A score of 2+ is a risk

40
Q

Other diagnoses with similar signs of DVT (differential diagnoses)

A

Lymphatic obstruction
Soft tissue trauma
Cellulitis

41
Q

Causes DVT (7)

A 
Stasis because no calf muscle pump 
Pre/Post surgery
Immobility 
Trauma - prothrombotic state following:
Malignancy
Pregnancy
42
Q

Decrease risk of DVT (4)

A
  • Promote mobility soon after surgery
  • Prophylaxis (anticoagulants post surgery)
  • Gradient stockings
  • Physical activity
43
Q

FATAL consequence of DVT

A

Pulmonary embolism

44
Q

What is the body’s way of reducing acute ischaemia risk when we flex joint?

A

Form collateral circulation (alternative routes to same destination)

45
Q

What is an adaptive response to stenosis of a major vessel over a period of months or years?

A

Form collateral circulation (alternative routes to same destination)

46
Q

What is acute limb ischaemia?

A

Occlusion occurs in minutes/days

No time for collateral circulation to form

47
Q

Causes of acute limb ischaemia (3)

A

Trauma and embolism e.g.:

Atrial fibrillation
Popliteal artery aneurysm
Sudden rupture of atherosclerotic plaque

48
Q

Signs and symptoms of acute limb ischaemia (6)

A 
The 6P's
Pain
Pallor
Perishingly cold
Pulseless
Paraesthesia
Paralysis

also increased capillary refill time

*may be subtle - compare both limbs
49
Q

Actions after ischaemia (7)

A
  • Immediate referral to vascular surgery unit
  • extent of threat of limb survival dictates action
  • image first then either:
  • Angioplasty (surgical repair or unblocking of a BV)
  • Thrombectomy
  • Intra-arterial thrombolysis or
  • Amputation
50
Q

If revascularisation is possible after acute limb ischaemia, what may be a complication?

A

Compartment syndrome

51
Q

What is chronic peripheral arterial disease similar to?

A

Coronary artery disease

52
Q

Describe Chronic peripheral arterial disease (3)

A
  • Intermittent claudication of the lower limb (cramping pain in calf muscle upon exercise)
  • Caused by atherosclerosis
  • Pain relieved by rest
53
Q

Management chronic peripheral arterial disease (claudication) (5)

A 
Exercise
Smoking cessation
Anti-platelet drugs
Angioplasty
Bypass graft
54
Q

What device do you use in Diagnosing peripheral vascular disease?

A

Ankle-Brachial Pressure Index

divide ankle systolic by brachial systolic, if <0.8 BAD

55
Q

Describe the use of an ABPI (3)

A
  • part of early diagnostics for peripheral artery disease
  • divide ankle systolic by brachial systolic
  • ABPI <0.8 suggests presence of PAD
56
Q

Untreated claudication becomes…

A

critical ischaemia

57
Q

Pathology of claudication

A
  • Mild, moderate and severe claudication
  • Then rest pain, ulcer, gangrene (when critical)
    ischaemia)
  • Most common presentation is Atheroma –> atherosclerosis of femoral artery
  • Present with calf claudication
  • Untreated becomes critical ischaemia (then you could get serious ulcers and gangrene)
58
Q

Critical limb ischaemia presentation

A 
Progression of peripheral vascular disease
REST PAIN (blood supply is so poor get pain when resting)

(hanging foot out of bed relieves pain)
(Strong pain relive needed at this stage)

59
Q

What can critical limb ishcaemia lead to?

A

Ulceration and gangrene

60
Q

How to identify location of occlusion is?

A

Which pulses can and cannot be palpated

61
Q

4 diff. lower limb pulses that you can palpate and their locations?

A 
1. Femoral pulse (mid inguinal point = midway between ASIS and pubic symphysis)

2. Popliteal pulse (deep in popliteal fossa)

3.Dorsalis Pedis pulse  (lateral to extensor hallucis longus tendon)

4. Posterior tibial pulse (behind medial malleolus)
62
Q

What scan is used in Diagnosing peripheral arterial disease?

Describe it’s uses

A

Doppler ultrasonography (estimates flow and velocity of blood)

Useful for measuring flow and velocity of blood - the sounds of blood movement are computed into flow and velocity and can be used to see whether there are any occlusions in the vessels

Velocity increases through stenosis then becomes turbulent

63
Q

Changing frequency doppler effect

A

Higher frequency waves (high pitch) if blood moving towards (more bunched up)

Lower frequency (lower pitch) waves if moving away (waves spread out)

64
Q

Doppler effect definition

A

Apparent change in frequency of a wave caused by relative motion between source of wave and observer

CVS 2023 (26 decks)

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