Acute coronary syndrome Flashcards
Main cause of acute coronary syndrome
Atheromatous plaque rupture
Other pathologies of acute coronary syndorome
- Coronary dissection (tear in tunica media)
- Coronary spasm
Assess for acute coronary syndrome
ECG and then measure troponin
NSTEMI ECG could be…
ST depression
Inverted T waves
Normal
How to meet diagnosis of acute MI?
Increase and/or decrease in cardiac biomarker preferably cardiac troponin
+ 1 of following:
Symptoms of ischaemia
New ST/T wave changes or left bundle branch block
Imaging evidence of wall abnormality (echocardiogram)
Angiography detects thrombus
Type 1 MI
Atheromatous plaque rupture, ulceration, fissure, erosion or dissection = thrombus decreasing myocardial blood flow/embolism and then necrosis
Type 2 MI
Other than coronary plaque creates instability between demand and supply of myocardial oxygen
Type 2 MI examples
Coronary artery spasm Coronary endothelial dysfunction Tachyarrhthmias/Bradyarryhthmias Anaemia Respiratory failure Hypotension Severe Hypertension
Assessment of suspected acute coronary syndrome
History: cardiac sounding? Radiation to neck/left arm/jaw? Relieved with GTN (glyceral trinitrate spray, vasodilator) How long/getting worse?
Risk factors present? (eg diabetes, smoker, high cholesterol, family history)
Examination MI
BP if systolic <90 = cardiogenic shock Tachy/Bradycardia (2:1 heart block/complete) JVP - distended (high pressure) Heart murmur Cool peripheries?
Inferior ECG leads
Lead 2
Lead 3
aVf
(right coronary artery)
Anteroseptal ECG leads
V1
V2
V3
V4
(left anterior descending)
Lateral ECG leads
Lead 1
aVL
(high lateral)
V5
V6
(left circumflex artery)
Anterior leads
V1-V6
left anterior descending
What leads affected if left coronary artery affected?
V1-V6 + aVL