Peripheral Vascular Disease Lecture Powerpoint Flashcards

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1
Q

Peripheral arterial disease

A

Atherosclerosis of blood vessels other than the coronary or cerebral arteries leading to obstruction

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2
Q

Atypical leg pain

A

Lower extremity discomfort that is exertional but does not consistently resolve with rest or consistently limit exercise at a reproducible distance making it different from intermittent claudication but still a finding in peripheral arterial disease

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3
Q

Intermittent claudication

A

Reproducible discomfort of a defined group of muscle that is induced by exercise and relieved upon rest, classic finding of peripheral arterial disease

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4
Q

Critical limb ischemia

A

Ischemic rest pain, a non healing wound, or gangrene due to progression from claudication resulting in severe peripheral arterial disease

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5
Q

The 5 P’s of acute limb ischemia that indicate severe peripheral arterial disease

A
Pain
Pulseless
Pallor
Paresthesias
Paralysis
Poikilothermia (the rare 6th P)
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6
Q

Ankle brachial index and value ranges

A
  • Division of the lower extremity systolic pressure by the brachial artery systolic pressure to determine if there is arterial disease causing claudication to the lower extremity
  • value of 1 is normal and values less than .8 indicate moderate to severe arterial disease
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7
Q

Absent femoral pulses can indicate ___ disease (peripheral arterial disease)

A

iliac artery

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8
Q

Gradation of pulse intensity on physical exam

A
0 - absent
1 - diminished
2 - normal
3 - strong
4 - bounding
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9
Q

Some common differential diagnoses of peripheral arterial disease (3)

A
  • degenerative joint disease
  • venous insufficiency
  • chronic compartment syndrome
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10
Q

Gold standard diagnostic for evaluation of peripheral arterial disease

A

Peripheral angiography

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11
Q

Treatment of peripheral arterial disease (6)

A
  • Statin
  • Antihypertensives
  • Aspirin or plavix (antiplatelet therapy)
  • Pletal (effective at improving symptoms and increasing walking distance in patients with PAD and claudication)
  • revascularization
  • amputation
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12
Q

Revascularization therapy

A

Indicated treatment in patients with significant or disabling symptoms unresponsive to lifestyle adjustment or medical therapy or in patients with limb threatening ischemia to establish arterial blood flow either by angioplasty (bipass), or stenting

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13
Q

Superficial varicosities

A

A very common form of peripheral venous disease that is due to inadequate muscle pump function, incompetent venous valves, or venous thrombosis and obstruction

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14
Q

Peripheral venous disease presentation vs peripheral arterial disease

A
  • Venous has leg swelling and aching

- Arterial has sharp intermittent pain

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15
Q

Treatment of peripheral venous disease (2)

A
  • leg elevation and compression socks

- surgical excision

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16
Q

Superficial phlebitis

A

Presence of pain and inflammation involving a vein in absence of a thrombus from venous stasis, procedures, infection, or IV therapy

17
Q

Unprovoked vs provoked and proximal vs distal DVTs

A

Unprovoked - no identifiable environmental event
Provoked - caused by known event such as surgery, hospitalization, immobility etc.

Proximal - within the popliteal, femoral, or iliac veins
Distal - below the knee and confined to calf veins (peroneal, posterior tibial, anterior tibial veins)

18
Q

Virchow’s triad

A
  • Hypercoaguable state
  • intimal trauma
  • venous stasis
19
Q

Upper extremity DVT

A

Rare form of DVT occurring in subclavian, axillary, or brachial veins

20
Q

Well’s score

A

System used to assess clinical probability of DVT with 0 points being low probability, 1-2 being moderate, and 3-8 being high probability

21
Q

D Dimer test for DVT

A

Elevated in nearly all patients with acute DVT so highly sensitive however picks up many false positives from any other clot formed in body, so should only be used to rule out DVT

22
Q

Postthrombotic syndrome (PTS)

A

Chronic venous insufficiency developed following DVT due to a combination of refulx due to valvular incompetence and venous hypertension from former thrombotic obstruction

23
Q

DVT prevention DOC

A

Low molecular weight heparin (no lab monitoring required, and has high bioavailability, only con is it has to be injected subQ)

24
Q

Treatment of DVT

A
  • Initial anticoagulants (LMWH, apixaban)
  • long term anticoagulation (warfarin, LMWH)
  • Thrombolytics (TPA)
25
Q

IVC filter

A

Used in patients who have contraindication to anticoagulant therapy for DVT prevention, used to catch clots