Peripheral Neuropathy Flashcards

1
Q

What is areflexia a cardinal sign of?

A

peripheral neuropathy

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2
Q

Which sensory modality tends to be lost first?

A

vibration

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3
Q

What are some signs of autonomic neuropathy?

A

postural hypotension

impaired gastric emptying

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4
Q

What is psuedoathetosis?

A

hands held out - fingers just start moving - loss of proprioception so they don’t know where they are in space

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5
Q

What is high stepping gait an indication of?

A

bilateral foot drop

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6
Q

What are the three subtypes of peripheral neuropathy?

A

mononeuropathy
mononeuritis multiplex
length dependent peripheral neuropathy

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7
Q

In what manner do nerves die off?

A

distal to proximal

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8
Q

What is a radiculopathy?

A

site of injury at the nerve root causing multiple neurological symptoms

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9
Q

What is a plexopathy?

A

neurological injury at a plexus

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10
Q

Which characteristic sign on EMG is seen in demyelination?

A

temporal dispersion

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11
Q

How does temporal dispersion arise?

A

responses arrive at different times causing phase cancellation

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12
Q

What is an example of an acute demyelinating neuropathy?

A

GBS

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13
Q

What is guillain-barre syndrome?

A

disorder in which the body’s immune system attacks part of the peripheral nervous system

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14
Q

Which common cause of food poisoning has an association with GBS?

A

campylobacter

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15
Q

How is GBS treated?

A

IV immunoglobulin

plasma exchange

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16
Q

Steroids are useful in GBS - T/F?

A

False

17
Q

What is hereditary neuropathy?

A

inherited condition causing peripheral neuropathy

18
Q

what is the most common genetic mutation causing HN?

A

CMT1a

19
Q

What are some causes of chronic autonomic neuropathy?

A

diabetes
amyloidosis
hereditary

20
Q

How is axonal peripheral neuropathy treated?

A

treat cause

symptomatic - physio, orthotics, neuropathic pain relief

21
Q

How is vasculitic PN treated?

A

Pulsed IV -
methylprednisolone
+
cyclophosphamide

22
Q

How is demyelinating PN treated?

A

IVIg
Steroids
azathioprine, mycophenalate
cyclophosphamide