Motor Neurone Disease

Question 1

What is MND?

Answer 1

untreatable and rapidly progressing neurodegenerative condition with muscle weakness +/- speech, swallowing and breathing problems

Question 2

Is MND an upper or motor motor neurone condition?

Answer 2

Both!

Question 3

Sensory signs are also present in MND - T/F?

Answer 3

False!

Question 4

What is the average survival time of MND?

Answer 4

3 years

Question 5

What are the potential sites of onset for MND?

Answer 5

extremities (70% - mostly lower MN)
bulbar (25%)
thoracic (2%)

Question 6

Are men or women more likely to have the bulbar variant of MND?

Answer 6

Women

Question 7

How is the diagnosis made?

Answer 7

diagnosis of exclusion

neurophysiology can extend findings

Question 8

What are the uses of neuroimaging and laboratory studies in MND?

Answer 8

to rule out other conditions

Question 9

What is ALS?

Answer 9

amyotrophic lateral sclerosis

Question 10

What is the differences in MND and ALS?

Answer 10

there aren’t any

Question 11

What is progressive muscular atrophy?

Answer 11

rare subtype of MND that only affects LMNs

Question 12

What is primary lateral sclerosis?

Answer 12

rare form of MND with a very slow onset over number of years

Question 13

What is FTD-MND?

Answer 13

syndromes of MND and frontotemporal dementia

Question 14

What common LMN signs are seen in MND?

Answer 14

weakness
wasting
fasciculations
hypotonia

Question 15

What common UMN signs are seen in MND?

Answer 15

hypertonia
spasticity
hyperreflexia
Babinski sign

Question 16

How is MND managed?

Answer 16

communication needs (SLT, tablets, technology)
nutritional needs (gastrostomy, dieticians)
respiratory needs (assessment, home ventilation)