Peripheral Nerve Injury Flashcards
what are traumas that cause injury to peripheral nerves?
Penetrating injury
Crush
Traction
Ischemia
Thermal
Percussion
Vibration
what causes laceration of PN’s?
glass, knife, fan, saw, metal or long bone fractures = 30% of serious nerve injuries
what PN is most commonly injured? 2nd most common?
ulner n.
median n.
what are the types of crush injuries?
- acute: arm impingement, immediate attention.
2. overuse crush: caused by overuse. double crush if 2 injured
what is a stretch injury?
Injury to the nerves of the neck and shoulder under high velocity that cause burning or stinging feeling
aka brachial plex injury
what can PNI cause?
Injury may result in demyelination or axonal degeneration,
Both can disrupt sensory and/or motor function
when does recovery occur in PNI?
When re-myelination with axonal regeneration occurs
AND re-innervation of sensory and motor receptors
what systems do PNI’s effect?
Motor
Sensory
Reflex
Autonomic
what is the anatomy of a PN (outer-inner)
Epineurial sheath (outside covering)
Epineurium (ground substance)
Bundle: perineurium
Fascicle: endoneurium (axon inside)
what are Seddons 3 levels of PNI?
- neuropraxia
- axonotmesis
- neurotmesis
what is neuropraxia?
least sever PNI
axonal continuity preserved, recovery rapid
only at site of injury
what is axonotmesis?
axons disrupted
recovery depends on distance from injury to end organ
spontaneous recovery
what is neurotmesis?
most sever
complete anatomical disruption
no spontaneous healing
what are Sunderlands 5 levels of PNI?
First Degree = Neuropraxia
Second Degree = Axonotemesis
Third Degree = Endoneurial covering severed
Fourth Degree = Perineurium disrupted
Fifth Degree = Complete disruption of nerve trunk, little hope of spontaneous recovery
where is the emphasis placed in sunderlands 5 levels of PNI?
fascicle structure of PN
what do response from sensory end organs depend on?
Atrophy
Degeneration
disappearance of PN
time spent detached (shorter recovery window)
what are the 3 most common sensory end organs?
Meissner Corpuscle
Merkel Cell
Pacinian Corpuscle
what are the implications of injured motor end organs?
Muscle atrophies, ceases to function
Progressive shrinkage of muscle fibers
longer window for recovery
what are internal forces of compression?
Tumors, fractures, callus