Peripheral Flashcards

1
Q

True or false

Exclude central processes, such as stroke or spinal cord injury, before considering an acute peripheral lesion.

A

True

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2
Q

What are hallmarks of cortical disease?

A

aphasia

apraxia, and

vision loss

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3
Q

These symptoms require further investigation for a central rather than peripheral disorder.

A

Lateralization of weakness,

hyperreflexia,

positive Babinski’s sign

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4
Q

is used to differentiate primary muscular or neuromuscular junction problems from peripheral nerve disorders.

A

Electromyography

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5
Q

measure the speed of conduction by observing the response to nerve stimulation by distally placed electrodes, can differentiate between axonal loss and demyelination

A

Nerve conduction velocity studies

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6
Q

are frequently required to confirm the diagnosis in acute or subacute inflammatory and infectious processes

A

Lumbar puncture and

cerebrospinal fluid analysis

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7
Q

For patients at risk for diaphragmatic failure, measure baseline ______________or _____________ in the ED to assess whether there is an immediate need for respiratory support or admission to an intensive care unit.

A

forced vital capacity or negative inspiratory pressure

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8
Q

Admit patients with acute peripheral neurologic ‘ conditions if there is _________,____________, ___________

A

potential respiratory or

autonomic compromise

severe or rapidly progressing weakness

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9
Q

If a peripheral disorder is suspected and the patient does not require admission, arrange for neurologic follow-up within __________ days

A

7 to 10 days

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10
Q

’ the most common cause of unilateral facial paralysis

A

Bell’s palsy

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11
Q

Cranial nerve VII, the facial nerve, supplies

A

motor innervation to the muscles of expression of the face and scalp and the stapedius muscle and taste to the anterior two thirds of the tongue

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12
Q

_________ virus may be the culprit in Bell’s palsy

A

herpes simplex

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13
Q

Idiopathic Bell’s palsy may be preceded by pain around or behind the

A

ear

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14
Q

Onset of facial paralysis is acute, with maxi- mal symptoms in

A

2 to 3 days

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15
Q

On exam, patients will have

A

facial droop, effacement of wrinkles and forehead burrows, and inability to completely close the eye

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16
Q

True or false

 Diagnosis of idiopathic Bell’s palsy is based on the history and physical exam and is a diagnosis of exclusion of other conditions that can cause facial palsy

A

True

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17
Q

most important alternative diagnoses to exclude are

A

ear infections and stroke

18
Q

True or false

When a central process causes facial paralysis, the forehead will be spared, as the forehead is supplied by cranial nerve VII arising near the pontomedullary junction, with crossed innervation. Peripheral facial nerve palsies will manifest as weakness throughout the facial nerve distribution, including the forehead.

19
Q

Treatment with__________ has shown significant benefit in the treatment of Bell’s palsy

A

corticosteroids

20
Q

True or false

Any patient with facial paralysis sparing the forehead or inability to abduct an eye should undergo neuroimaging to assess for stroke.

21
Q

Compare and contrast middle cerebral artery stroke and brainstem stroke

A

Middle cerebral artery ischemia or stroke consists of hemiparesis, facial plegia sparing the forehead, and sensory loss all contralateral to the affected cortex.

Rarely, a brainstem stroke may mimic Bell’s palsy if the stroke affects the area where the facial nerve wraps around the abducens (cranial nerve VI) nucleus.

Brainstem stroke findings include peripheral facial nerve palsy and ipsilateral gaze palsy due to ischemia of the abducens nucleus.

So, test extraocular muscle function in all patients suspected of having Bell’s palsy.

22
Q

In Bell’s palsy, most patients begin to recover within

23
Q

True or false

 Evidence from randomized controlled trials suggests a benefit when giving antiviral medications in combination with steroids over steroid therapy alone.

25
acute polyneuropathy characterized by immune-mediated peripheral nerve myelin sheath or axon destruction
Guillain-Barré syndrome
26
Pathology of Guillain-Barré syndrome
antibodies directed against myelin sheath and axons of peripheral nerves are formed in response to a preceding viral or bacterial illness
27
Common infectious precipitants in GBS
Campylobacter jejuni, Zika virus, Cytomegalovirus, Epstein-Barr virus, or Mycoplasma pneumoniae
28
True or false GBS is thought to be associated with antiganglioside antibodies
True
29
GBS variant lymphocytic infiltration of the myelin sheath
demyelinating form
30
GBS variant motor paralysis with sensory function intact
axonal form
31
Miller-Fisher syndrome variant is characterized by
ophthalmoplegia, ataxia, and areflexia
32
Csf fluid of GBS
high protein levels (>45 milligrams/dL) WBC counts typically <10 cells/mm3 with predominantly mononuclear cells
33
GBS Electrodiagnostic testing demonstrates
demyelination
34
Nerve biopsy reveals a
mononuclear inflammatory infiltrate
35
GBS MRI shows
enhancement of affected nerves
36
Identify
Erythema chronicum migrans rash
37
Identify
Herpes zoster oticus
38
True or false Ramsey Hunt syndrome is a herpes zoster infection of the geniculate ganglion
True
39
Identify
Ramsay hunt syndrome
40
Identify
Phalen’s test
41
Identify
Phalen’s test