Peripartum Infection

Question 1

Which of the following is not part of the diagnostic criteria for intra-amniotic infection?

A) maternal temperature of ≧ 39℃
B) fetal tachycardia
C) maternal tachycardia
D) purulent cervical drainage
E) maternal leukocytosis

Answer 1

C) maternal tachycardia

Question 2

What is the preferred antibiotic regimen for treatment of intra-amniotic infection?

Answer 2

Ampicillin 2g IV every 6 hours and Gentamicin 5mg/kg every 24 hours or 2mg/kg IV load by 1.5mg/kg every 8 hours

Question 3

What are risk factors for neonatal sepsis?

Answer 3

Maternal fever, infant prematurity, prolonged rupture of membranes

Question 4

What is the definition of isolated maternal fever?

Answer 4

Either a single oral temperature of ≧ 39℃ or 38-38.9℃ that persists when temperature repeated after 30 minutes with no additional risk factors

Question 5

What is the neonatal morbidity associated with intra-amniotic infection?

Answer 5

Neonatal pneumonia
Bronchopulmonary dysplasia
Cerebral palsy
Meningitis
Sepsis
death

Question 6

What is the recommended antibiotic regimen for a patient diagnosed with intra-amniotic infection with mild penicillin allergy?

Answer 6

Cefazolin 2g IV every 8 hours and Gentamicin5mg/kg IV every 24 hours or 2mg/kg IV load by 1.5mg/kg every 8 hours

Question 7

What is the recommended antibiotic regimen for a patient diagnosed with intra-amniotic infection with severe penicillin allergy?

Answer 7

Clindamycin 900 mg IV every 8 hours or Vancomycin 1g IV every 12 hours
and Gentamicin 5mg/kg IV every 24 hours or 2mg/kg IV load by 1.5mg/kg every 8 hours