Perioperative Medicine Flashcards

1
Q

What to do for patient at high cardiac risk (>65 or 18-64 and known CAD, cerebrovascular dz, PAD, CHF, PH, AS/MS/HoCM) going for emergency “A Case” Surgery ie life/limb in 6 hrs (trauma, AAA rupture, nec fasc)

A

DO NOT DELAY
Continue ASA if on already and okay’d by surgeon
Continue BB
Post-op: PACU ECG, Trop x72 hrs daily, shared care

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2
Q

What to do for patient at high cardiac risk going for Urgent (w/i 24-48h eg SBO, hip #) or Semi-Urgent (eg cancer) OR?

A

Delay only if:

  • ACS
  • Unstable arrhythmia
  • Unstable CHF exacerbation
  • Suspicious of severe pHTN or AS (try to get echo 1st)
Continue ASA (if surgeon permits) + BB if already on
Post-op: PACU ECG, Trop x72 hrs daily, shared care
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3
Q

What do for patient at high cardiac risk going for elective OR?

A

If high risk stress test or unstable CAD or suspicion of severe AS - delay OR for testing

If not:
If RCRI = 0 + Age <65 + No CVD - proceed with OR
If RCRI>0 or Age>=65 or major CVD: Obtain pre-op BNP
- If elevated or not avail: PACU ECG, Trop x72 hrs daily, shared care
- If not elevated: Proceed to OR with no further testing

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4
Q

RCRI Score and cardiac risk assessment

A

Surgical risk + 4C’s and a D:

  • High risk OR (intra-thoracic, intra-abdominal, supra-inguinal vascular)
  • CHF (S3, crackles, pulm edema, PND, +CXR)
  • CAD - +stress test, Q waves, angina, nitrate use, hx MI (NO points if asx w/ PCI/CABG)
  • CVD - TIA/stroke
  • CKD - Cr > 177
  • DM - insulin dependent
0 = 4% risk peri-op CV event (MI, CHF, VF, death) 
1 = 6%
2= 10% 
3+= 15%
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5
Q

Management of anti-platelets with stents peri-op for elective OR

A

Delay 14 ds post POBA, 1 mo post BMS, 3 mo post DES
Continue ASA if possible (if permitted by surgeon)
Stop 2nd anti-plt 5-7 days pre-op

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6
Q

Management of anti-platelets with stents peri-op for urgent or emergent OR

A

Continue ASA
Hold 2nd anti-platelet
Monitored bed post-op

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7
Q

Management of suspected severe stenotic valve disease pre- elective surgery

A
  1. Obtain TTE if suspected mod-sev stenosis/regurg and no TTE on record within 1 year or change in status since last echo
  2. If meets criteria for valve surgery –>replace/repair before elective surgery
  3. If demonstrates low flow low gradient severe AS (AVA <1cm, MG <40, Vp <4, LVEF <50%) –> refer for dobutamine stress test (and for AVR if +) pre-op
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8
Q

Management of suspected severe stenotic valve disease pre- urgent surgery

A

Do not delay, but attempt to obtain TTE while OR awaits
Inform anesthesia
Intra-operative monitoring
Post-op monitored bed

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9
Q

Treatment of Myocardial Injury after Non-Cardiac Surgery (MINS)

A
Type 1 (plaque): revasc, DAPT, high dose statin, BB, ACE/ARB
Type 2 (demand mismatch): ASA, statin, noninvasive testing
Shared care - surgeons, IM, cardio
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10
Q

Risk factors for post-operative respiratory failure

A

Lung dz: COPD/asthma (continue pufers), pHTN

Comorbidities: CHF, COVID, OSA/Obesity, Smoking (>4wks cessation = benefit),

Frail: Age >60, Alb <35, poor health/fcnal health status

Surgery:

  • Intrathoracic > Intraabdo surgery
  • Surgery under GA
  • Long OR
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11
Q

Mitigating resp risk post-op

A

Pain control
DVTp

Incentive spirometry
Early mobilization
NG decompression

Continue home CPAP
Consider extubating to NIPPV

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12
Q

Management of BB peri-op

A

Continue if already on

Don’t start within 24 hrs of OR (except if unstable arrhythmia)

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13
Q

Management of ASA peri-op

A

Don’t initiate
Continue if going for CEA
Continue if cardiac stents (definitely if <1m BMS/3m DES, beyond - shared discussion)
Otherwise, discontinue at least 3 days pre-op
Resume as soon as safe per surgeons

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14
Q

Management Plavix/Ticag peri-op

A

Hold 5-7 days pre-elective surgery (7 if neuraxial anesthesia)
If urgent OR and new stent - discuss continuation with surgeon
If urgent OR and old stent - hold
Resume as soon as safe per surgeons
If <3-5 days = no neuraxial anesthesia

for prasugrel (7-10 dep on neuraxial anesthesia)

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15
Q

Management of statin peri-op

A

Continue

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16
Q

Management of ACE/ARB peri-op

A

Hold 24 hrs pre-op

Resume on POD2 if eating/drinking well, not hypotensive and no AKI

17
Q

Indications to hold anti-coagulation before elective OR

A

All procedures except:

  • Minor dental (<=2 teeth extraction, periodontal, root canal, teeth cleaning) - use oral prohemostatic agent
  • Minor derm eg skin bx
  • Cataracts
  • Endoscopy WITHOUT biopsy
18
Q

Indications to bridge warfarin peri-operatively for elective surgery

A

1) Afib with:
- CHADS2 5/6
- rheumatic or mechanical valve
- stroke in last 3 months

2) Valves (all mechanical, all mitral, old AVR eg ball/cage, tilting disk) if 1+ of:
- Afib
- LV dysfunction
- Past embolism
- Hypercoagulable state
- Stroke w/i 6 mo

3) VTE :
- Within 3 months
- High-risk thrombophilia: APLA, Protein C/S/ATIII def, or multiple

19
Q

Management of DOAC Pre-elective surgery

A

Apix/Riva/Edox
Hold x48 hrs pre-op if high risk bleed (OR day -2)
Hold x24 hrs low risk bleed (OR day -1)

Dabi
Hold x4 days pre-op if high risk bleed
Hold 2 days (48 hrs) pre-op if low risk bleed

*If CrCl <30 - add 24 hours to hold

Resume as soon as safe per surgeons

20
Q

Management of Warfarin Pre-elective surgery

A

Hold for 5 days pre-op (OR Day -5), check INR pre-op D1

If bridging / high risk of thrombosis:

  • Start LMWH 3 days pre-op - therapeutic dose on pre-op day 3 and 2, 1/2 therapeutic dose pre-op D1
  • Hold LMWH on day of OR

Start warfarin at 1.5x home dose 12 hours post-op and resume LMWH 24 hrs post-op (if ok by surgeons)

Continue LMWH until INR therapeutic

21
Q

Management of anti-rheumatic drugs peri-op elective OR

A

Continue all DMARDs

Hold biologics 1 dosing cycle pre-op and resume once evidence of adequate wound healing

22
Q

Management of SGLT-2 inhibitors peri-op

A

Hold 3 days pre-operatively

23
Q

Management of all non-SGLT2 oral anti-glycemics peri-op

A

Hold on day of OR and use SS

24
Q

Management of insulin peri-operatively

A

Take 70-100% qhs or 1/2 of AM basal insulin dose (lantus/ tuojeo/ tresiba/ nph/ levemir/ mix 70:30)
-Hold all short acting

IV insulin infusion peri-op if:

  • Long OR (1-2h) in IDDM or T1DM
  • CABG or major OR (target 5.5-11.1 vs minor OR 5-10)
  • Intrapartum for IDDM
25
Q

VTE Prophylaxis post-op

A

NO meds, use IPC>compression stocking for:

  • Neurosurg,
  • CV/Vasc surg (equivocal),
  • Urologic,
  • Major Trauma,
  • Lap Chole
  • All other inpatient surgeries: LMWH/UFH x 19-42 days (or until D/C for minor)
  • Postop ppx for all pregnant patients
  • No LMWH for 4 hours, Fonda for 6-12h, Heparin for 1h after neuraxial anesthesia removed
26
Q

Indications to give stress dose steroids perioperatively

A

Major surgery +

1) Prednisone >=20 mg/day for >=3 weeks
2) Prednisone 5-20 mg x >=3 wks (consider)
3) Cushingoid features

27
Q

Stress steroid dosing

A
  • Major surgery (CV, liver resection, whipple): Usual AM dose +HC 100mg IVX1 pre-op, then 50 mg q8hX3doses, then 25 mg q8h X 3 doses then back to usual dose
  • Moderate surgery (chole, hemicolectomy): Usual AM dose+HC 50mg X 1 pre-op, 25mg q8hX3, then usual dose
  • Minor surgery–Usual AM dose
28
Q

Peri-operative care for dialysis patients

A

Elective: Schedule for 1 day post-IHD, obtain K day of OR, should be <5.5 (otherwise no paralysis)

Urgent/Emergent: K pre-op, post-op monitored bed

29
Q

High risk features on noninvasive stress test

A
  • > 2mm ST depression
  • ST elevation,
  • VT/VF,
  • Failure of sBP >120 or BP drop >10 mmHg,
  • Ischemia >3min into recovery
  • EF<35%
  • Severe stress induced LV dysfunction - EF <45% or decrease with stress by over 10%
30
Q

MINS Definition

A

Troponin increase >99th percentile of ULN w/i 30d of surgery
Increase in 4th gen trop >0.03ng/mL, hsTnT 20-65ng/L w/ absolute change of >5, or any abs change >14 or any elevation over 65ng/L

Symptoms/ECG changes not required

31
Q

Screening for MINS

A

Adults >65y o adults >45 w established CAD/PAD

Preop baseline trop and postop 48-72h

32
Q

Managing AC for emergent/urgent/nonurgent surgeries

A

Emergent:

  • VKA: Vit K 5-10IV +/- PCC/aPCC
  • DOAC: antidote or PCC/aPCC if unavail

Urgent:

  • VKA: defer 12-24h if possible, give Vit K 2.5-5mg
  • DOAC: defer surgery 12-24h (if possible)

Nonurgent:
- Decide if need to bridge

33
Q

Preop/Intraop Anemia Mx

A

Optimize Hgb preop if <115 (F), <130 (M), <130 before major arthroplasty:

  • Iron: min 3-4d for effect
  • EPO: min 2-4wk for effect. Use in CKD, anemia chronic dz, refusing transfusion

Intraop:

  • TXA or ortho/liver sx or postpartum hemorrhage
  • Autologous transfusion
34
Q

Indication for pre-op CXR/PFT

A
  • PFT if one lung ventilation planned

- To predict need for postop ventilation in neuromuscular dz

35
Q

Jehovah’s Witness Blood Approach

A
  • Decrease phelebotomy (freq, pediatric tubes)
  • Autologous blood donation, Fe, EPO preop
  • TXA, DDAVP
  • Acute normovolemic hemodilution (for high risk bleed OR: major cardiac, ortho, thoracic, liver)
  • RBC salvage (not if sepsis, Ca, bone cement)
  • Hgb based O2 carriers
36
Q

OSA Periop

A
  • Anesthesia and Surg to decide if delay for sleep study (eg invasive surgery or post-op opioid needed)
  • In vs outpatient OR
  • Bring CPAP if on it, if unresponsive, consider BIPAP
  • Regional/local anesthetic to limit sedation and post-op opioids
  • Non-supine position post-OR if possible
37
Q

ICD Mx

A
  • Reprogram pre-op if surgery above umbilicus w/ cautery use to avoid shocking patient/surgeon
  • Suspend anti-tachy therapy and/or initiate asynchronous pacing with magnet