Perinatal infection Flashcards
obstetric history
Other medical problems Social problems Problems in this pregnancy Results of antenatal investigations Delivery (PROM, maternal fever / ABx) Current condition Medications
obstetric examination
Resp distress (grunting, recession) altered behaviour/responsiveness poor feeding floppy temperature instability jaundice/organomegaly/rash/growth impairment
investigations in perinatal infection
microbiology:
FBC, LFTs, blood culture, CRP, CSF, serology, urine
imaging:
CXR
immediate treatment in perinatal infection
antibiotics: benzyl penicillin, gentamicin
antivirals: acyclovir
antifungals
NICU/cardiorespiratory monitoring/blood gas/ respiratory support/IV access
bacterial causes of fetomaternal infection
Group B streptococcus Enterobacteriaceae Bacterial vaginosis Chlamydia Gonorrhoea Listeria Syphilis
viral infection
intrauterine infection
CMV, parvovirus, rubella, HIV
peri/post natal infection Varicella-zoster virus Herpes simplex Hepatitis B HIV Hepatitis C Enterovirus
red flags for risk of early onset neonatal infection
Maternal sepsis within 24 hrs of the birth
Suspected infection in a co-twin
Mechanical ventilation in a term infant
Seizures
Shock
Respiratory distress starting >4 hours after birth
CHEAP TORCHES
congenital infection
Cytomegalovirus Herpes simplex Enteroviruses AIDS Parvovirus B19
Toxoplasmosis Rubella Chickenpox Hepatitis B&C Everything else sexually transmitted Syphilis