Pericardial Disease Flashcards
Most common cause of acute pericardial disease?
Idiopathic
Causes of Pericarditis
Radiation Neoplasm Trauma Autoimmune Metabolic (Hyperthyroidism, Uremia)
Viral causes of Pericarditis?
Coxsackie A or B, Echovirus, Mumps, Adenovirus, and HIV
Bacterial causes of Pericarditis?
TB, pneumococcus, streptococcus, staphylococcus, legionella
Fungal causes of Pericarditis?
Histoplasmosis, Coccidiomycosis, Candidiasis, Blasto
Cardiac causes of Pericarditis?
Early infarction pericarditis
Late post cardiac injury (Dresslers’)
Myocardiits
Dissecting aortic aneurysm
Drugs that cause Pericarditis?
Procainamide
Isoniazid
Hydralazine
Acute Pericarditis pathologic anatomy
Usually fluid accumulation – usually serous
Bacteria (Purulent) and Tumor Cells
Fluid may resolve or form adhesions
Chronic Pericarditis pathologic anatomy
Roughened Heart Surface
Bread and Butter
Clinical Features of Pericarditis?
Chest Pain
Pericardial Friction Rub
ECG Changes
Pericardial Effusion
Acute Pericarditis Chief Complaints
Chest Pain unrelated to exertion
Fatigue, Dyspnea, Malaine
Fever
Describe the chest pain of Acute Pericarditis?
Sharp, Stabbing, Sudden Onset
Worse on deep inspiration and lying flat
Better Leaning Forward
Describe a Pericardial Rub
From friction btw layers of pericardium
Superficial, scratchy, leathery sound – higher than diastolic filling sounds
Best heard over left sternal border
Acute pericarditis findings
Typical history, exam ECG
Normal CXR most of the time
Autoimmune serologies
Pericardiocentesis if you suspect infection or cancer
What EKG changes are expected with Acute Pericarditis? (Overall)
Sinus Tachy Diffuse Concave ST changes PR depression PR elevtion+ST depression in aVR Diffuse -- not associated with a specific vessel
EKG changes 4 stages
- Hours to Days - Diffuse ST Elevation, PR depression
- First week – Normalization of ST and PR
- Diffuse T wave inversions
- Normalization of EKG or indefinited persistence of inversions (in chronic)