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Antibiotics > Peptidoglycan Interfering Antibiotics > Flashcards

Peptidoglycan Interfering Antibiotics Flashcards

0
Q

Vancomycin Use

A
  • Gram + only
  • Serious multi drug resistant organisms
    1. S. aureus
    2. enterococci
    3. C. Difficile
    4. Oral dose for pseudomembraneuos colitis
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1
Q

Vancomycin Mechanism

A
  • Inhibits cell wall mucopeptide formation
  • Binds D-ala-D-ala portion of cell wall precursors
  • Bactericidal
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2
Q

Vancomycin Toxicity

A
  • Nephrotoxicity
  • Ototoxicity
  • Thrombophlebitis
  • Diffuse flushing: red man syndrome
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3
Q

Vancomycin Resistance

A

-AA change from D-ala D-ala to D-ala D-lac

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Antibiotics (9 decks)

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