Peptic Ulcers Flashcards
List the five aggressive factors for peptic ulcer.
Two are familiar, pepsi rots your guts, one is a drug, another is guessable.
Helicobacter pylori Smoking Acidity NSAIDs Pepsin
List the five aggressive factors for peptic ulcer.
No prompts.
H. pylori Acidity Smoking Pepsin NSAIDs
List the four protective factors against peptic ulcers.
One is about supply, one is snotty, one is diminished by the “aggressive” drug type, one is about pH
Bicarbonate
Blood flow
Mucus
Prostaglandins
List the four protective factors against peptic ulcers.
No prompts
Bicarbonate
Blood flow
Prostaglandins
Mucus
How prevalent is H. pylori in the population?
40-90%
How many gastric ulcer patients have H. pylori infections? What makes up the remainder?
70%
Remainder is NSAIDs
How many duodenal ulcers are infected with H. pylori?
90%
How does H. pylori live in the stomach?
Urease produces basic NH3 from water and urea, neutralising the surrounding juices.
How does giving a patient some 13C-urea to eat let us test for H. pylori?
The H. pylori will produce 13CO2 from the 13Curea
What are the four pharmaceutical pillars of PU treatment?
Antibiotics, anti-secretory agents, antacids, mucosal protectants
Constipation, systemic alkalosis, diarrhoea. In order, which three antacids cause these?
Aluminium hydroxide, sodium bicarbonate, magnesium hydroxide.
The characteristic side effect of cemitidine is R and ranitidine is Q.
anti-andrenergia; pneumonia.
What are the two H2-blockers?
Cemitidine, ranitidine
What is the mucosal protective drug?
COLLOIDAL BISMUTH SUCRAFATE. Don’t worry about confusing it with sulfate. It’s all multiple choice.
Just don’t confuse it with bismuth subsalicylate (the antacid pepto-bismol).
What’s the only PPI mentioned?
Omeprazole
