Peptic Ulcer Disease Flashcards
What is peptic ulcer disease
A condition characterised by ulcerations on the GI mucosa and inner layers due to acidic gastric secretions
Where do chronic peptic ulcers tend to occur?
Lesser curvature of stomach by pylorus
Why does the erosion happen
Due to the lining not being able to protect againts HCl and pepsin due to either and increase in conc or activity level of HCL OR a decrease in the resistance of the mucosa(unable to act as a barrier)
Why might vommitting occur?
Due to an obstruction of gastric outlet
How does haemorrhage of the ulcer happen?
Erosion of the granulation tissue found at the base of the ulcer. It can erode into a major blood vessel.
Symptoms of obstruction
Pain following eating
Severe anorexia
Vomiting large amounts regularly
Acid-base imbalance
What are symptoms of a perforated duodenal ulcer?
Sudden severe abdo pain
Decreasing bowel sounds
Pain radiating to shoulders
