IBD Flashcards
What is IBD
It is a group of chronic, progressive and complex inflammatory disorders or the digestive tract where the intestines become inflamed
What is the incidence of (i) crohns (ii)UC annually in ireland
(i) 12.7 per 100,000 persons
(ii) 24.3 per 100,000 persons
Approx how many people have IBD in ireland?
20,000 but could be up to 40,000
How many people worldwide are affected by IBD?
5 million people
How many people have IBD in Europe?
2.5-3 million people
Define Crohn’s disease?
It is a chronic condition which is lifelong with periods of remission as well as relapse. It can affect any part of the GI tract and is described as having a cobble stone/skip lesion appearance
Define ulcerative colitis
UC is restricted to the large intestine and appears as a continuous inflammation.
What does the inflammatory response lead to?
It leads to swollen, inflamed and ulcerated intestines. Deeper inflammation into the tissue can lead to perforation of the bowel
Name is types of ulcerative colitis
Pan colitis
Subtotal colitis
Distal colitis
Proctitis
What is the difference in the depth of involvement of uc and crohns?
UC: mucosa and submucosa
Crohns: total thickness of bowel wall
How is (i)UC (ii)crohns distributed
(i)continuously
(ii)segmentally
Name the types of crohns
Inflammatory
Stenosing
Penetrating/fistulsing
What is the most common extra intestinal manifestation?
Joints ie arthritis
What are the main symptoms of IBD?
Reaccurrent diarrhoea/loose stools
Blood/mucous in stools
Abdominal pain/cramps *after eating
Nausea and vomiting
Anemia
Retardation in children
Fever in severe cases
How does IBD affect the skin?
It can cause pyoderma gangrenosum and erethma nodostum
