Pentose Phosphate Shunt

Question 1

the oxidative portion of the shunt is the

Answer 1

1st 3 steps of the pentose phosphate shunt; irreversible

Question 2

nonoxidatice phase is

Answer 2

the last 5 steps of the pathway; generates Ru5P; reversible pathway

Question 3

the oxidative and nonoxidative pathways are important because

Answer 3

they allow for the synthesis of the different ratios of NADP and R5P

Question 4

the difference between transketolases and transaldolases

Answer 4

transketolases transfer 2 and transaldolases transfer 3

Question 5

How many NAPDH are produced for 1 GAP?

Answer 5

6

Question 6

Glucose 6P + NADP–> 6-phosphoglucono-delta-lactone + NADPH

Answer 6

Glucose 6P dehydrogenase
NADP
oxidation

Question 7

6-phosphoglucono-delta-lactone + H20–> 6-phosphogluconate

Answer 7

6-phosphogluconolacotnase
no cofactor
hydrolysis reaction

Question 8

6-phosphogluconate + NADP–> Ru5P + NADPH + CO2

Answer 8

6-phosphogluconate dehydrogenase
NADP
oxidation and decarboxylation

Question 9

Ru5P R5P

Answer 9

rubulose5P isomerase

isomerizaation

Question 10

Ru5P xylulose5P

Answer 10

Ru5P epimerase

Question 11

Ribose 5P + xylulose 5P glyceraldehyde 3P + sedoheptulose 7P

Answer 11

transketolase
TPP
intermolecular transer of a C2 unit

Question 12

glyceraldehyde 3P + sedoheptulose 7P–> F6P + erythose 4P

Answer 12

transaldolase
no cofactor
tintermolecular transfer of a 3 carbon unit

Question 13

erythose 4P + xylulose5P F6P + G3P

Answer 13

TPP

intermolecular transfer of 2-C unit