Pentose Phosphate Pathway

Question 1

3 functions of Pentose Phosphate Pathway

Answer 1

1. produce NADPH (power of fatty acids)
2. Produce R5P (synthesis is nucleotides)
3. Entry point for dietary pentose sugars

Question 2

Which tissues have active ppp?

Answer 2

adrenal, testes, ovary (steroid synthesis)

liver, adipose, mammary glads (fatty acid synthase)

Question 3

8 reactions in PPP (simple)

Answer 3

3 involve G6P>R5P

4. convert R5P>XU5P
5. convert RU5P>R5P

3 involver intervonversions of the last 2 reactions

Question 4

rate-limiting step of ppp

Answer 4

G6P by G6P dehydrogenase

Question 5

2 phases of ppp and their major product

Answer 5

1. oxidative (NADPH)

2. non-oxidative (R5P)

Question 6

where does the ppp take place

Answer 6

cytosol

Question 7

4 modes of ppp

Answer 7

1. mainly only R5P needed
2. NADPH and R5P needed
3. mainly only NADPH needed
4. NADPH and ATP needed

Question 8

what is transketolase’ synthetic group?

Answer 8

TPP