Penicillins

Question 1

What are 5 facts about narrow spectrum PCN VK and PCN G?

Answer 1

1. Gram + activity against step.pyogenes, steo agalactiae, enterococcus (pharyngitis and syphilis)
2. Activity against gram - neisseria meningitidis
3. Activity against T. Pallindum (syphillis)
4. Not activity against staph aureus (have penicillinase activity), neisseria gonorrhoeae, step. pneumoniae
5. Good for oral infections

Question 2

What are 4 facts about oxacillin?

Answer 2

1. Used for staph aureus
2. NO activity against enterococci, gram -, MRSA, ORSA, pneumonococci
3. Used for serious infections with OSSA and MSSA
4. Avaible IV and oral (dicloxacillin)

Question 3

What are 4 facts about Amp and Amox?

Answer 3

1. Intermediate spectrum with some activity against gram - (H. influenzea, E.coli)
2. mroe activity against entercoccus and listeria monocytogenes
3. Amox good for bronchitis, pharyngitis, otitis media
4. Amp good for meningitis due to secondary infections of listeria monocytogenes and bacterimia secondary to entercoccus
5. Not activity against pseudomonas

Question 4

What are 4 facts ahout Piperacillin tazobactam?

Answer 4

1. Gram - organisms including aeruginosa and enterobacter
2. Active against streptococci
3. Good for bowel infections because active against anaerobe
4. Good for hospital acquired infections

Question 5

What are 4 facts about Amp + Sulbactam and Amox + clavulanate?

Answer 5

1. activity against S. aureus, H. influ, E. coli
2. Activity against oral and gut anaerobes (peptostreptococcus and bacteroides
3. no activity against pseudomonas
4. good for gut and bowel infections, skin and soft tissue infections, human bite wounds, community acquire infections